Geriatric Medicine Center, Key Laboratory of Endocrine Gland Diseases of Zhejiang Province, Department of Endocrinology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.
Endocrine. 2022 Nov;78(2):241-246. doi: 10.1007/s12020-022-03119-3. Epub 2022 Jun 25.
The COVID-19 pandemic has posed a significant health threat globally. Timely and appropriate vaccination is a key step to reduce the morbidity and mortality from COVID-19. The clinical course of COVID-19 infection and the effects of COVID-19 vaccination are influenced by patients' health situations and involve a systemic physiological reaction. Just like an "endocrine phenotype" of COVID-19 infection, endocrine dysfunction after COVID-19 vaccination also acquired clinical concerns. In the present review, we briefly introduce the commonly available vaccines against SARS-CoV-2, summarize the influence of COVID-19 vaccines on the endocrine system, and explore the underlying pathogenic mechanisms.
新型冠状病毒肺炎(COVID-19)大流行对全球健康构成了重大威胁。及时、恰当的疫苗接种是降低 COVID-19 发病率和死亡率的关键步骤。COVID-19 感染的临床过程和 COVID-19 疫苗的作用受到患者健康状况的影响,并涉及全身生理反应。就像 COVID-19 感染的“内分泌表型”一样,COVID-19 疫苗接种后的内分泌功能障碍也引起了临床关注。在本综述中,我们简要介绍了目前可用的针对严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)的疫苗,总结了 COVID-19 疫苗对内分泌系统的影响,并探讨了潜在的发病机制。