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新型冠状病毒疫苗对内分泌系统的影响。

Influence of COVID-19 vaccines on endocrine system.

机构信息

Geriatric Medicine Center, Key Laboratory of Endocrine Gland Diseases of Zhejiang Province, Department of Endocrinology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.

出版信息

Endocrine. 2022 Nov;78(2):241-246. doi: 10.1007/s12020-022-03119-3. Epub 2022 Jun 25.

Abstract

The COVID-19 pandemic has posed a significant health threat globally. Timely and appropriate vaccination is a key step to reduce the morbidity and mortality from COVID-19. The clinical course of COVID-19 infection and the effects of COVID-19 vaccination are influenced by patients' health situations and involve a systemic physiological reaction. Just like an "endocrine phenotype" of COVID-19 infection, endocrine dysfunction after COVID-19 vaccination also acquired clinical concerns. In the present review, we briefly introduce the commonly available vaccines against SARS-CoV-2, summarize the influence of COVID-19 vaccines on the endocrine system, and explore the underlying pathogenic mechanisms.

摘要

新型冠状病毒肺炎(COVID-19)大流行对全球健康构成了重大威胁。及时、恰当的疫苗接种是降低 COVID-19 发病率和死亡率的关键步骤。COVID-19 感染的临床过程和 COVID-19 疫苗的作用受到患者健康状况的影响,并涉及全身生理反应。就像 COVID-19 感染的“内分泌表型”一样,COVID-19 疫苗接种后的内分泌功能障碍也引起了临床关注。在本综述中,我们简要介绍了目前可用的针对严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)的疫苗,总结了 COVID-19 疫苗对内分泌系统的影响,并探讨了潜在的发病机制。

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