Kojimahara M
Acta Pathol Jpn. 1986 Oct;36(10):1477-85. doi: 10.1111/j.1440-1827.1986.tb02819.x.
Seven cases of cavernous hemangioma of the liver found accidentally at autopsy were studied by electron microscope. The structures of the hemangioma consisted of capillaries and the intervening stromal cells. The endothelial cells contained pinocytotic vesicles, scattered ribosomes, rough endoplasmic reticulum, and Golgi apparatus. A distinct basement membrane was present beneath the endothelial cells, and multilaminated arrangement of the basement membrane was sometimes observed beneath the endothelial cells. The endothelial cells also contained numerous cytoplasmic filaments, but contained sparse specific endothelial granules. The internal elastic lamina was hardly seen at all in the hemangioma. The stromal cells showed typical smooth muscle cells, modified smooth muscle cells, and fibroblast-like cells. Elastic tissue as well as collagen fibers was present within the intervening stroma. Neither adventitia nor nerve fibers were found in the cavernous hemangioma. It is thought that cavernous hemangioma of the liver may be of a hamartomatous nature.
对7例尸检时偶然发现的肝脏海绵状血管瘤进行了电子显微镜研究。血管瘤的结构由毛细血管和其间的基质细胞组成。内皮细胞含有吞饮小泡、散在的核糖体、粗面内质网和高尔基体。在内皮细胞下方有一层明显的基底膜，有时在内皮细胞下方可见基底膜的多层排列。内皮细胞还含有大量的细胞质细丝，但含有稀疏的特异性内皮颗粒。在血管瘤中几乎完全看不到内弹性膜。基质细胞表现为典型的平滑肌细胞、改良的平滑肌细胞和成纤维细胞样细胞。在其间的基质中存在弹性组织以及胶原纤维。在海绵状血管瘤中未发现外膜和神经纤维。认为肝脏海绵状血管瘤可能具有错构瘤的性质。
