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使用两阶段深度学习方法从日本放射学报告中提取临床信息:算法开发与验证

Extracting Clinical Information From Japanese Radiology Reports Using a 2-Stage Deep Learning Approach: Algorithm Development and Validation.

作者信息

Sugimoto Kento, Wada Shoya, Konishi Shozo, Okada Katsuki, Manabe Shirou, Matsumura Yasushi, Takeda Toshihiro

机构信息

Department of Medical Informatics, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan.

Department of Transformative System for Medical Information, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan.

出版信息

JMIR Med Inform. 2023 Nov 14;11:e49041. doi: 10.2196/49041.

DOI:10.2196/49041
PMID:37991979
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10686535/
Abstract

BACKGROUND

Radiology reports are usually written in a free-text format, which makes it challenging to reuse the reports.

OBJECTIVE

For secondary use, we developed a 2-stage deep learning system for extracting clinical information and converting it into a structured format.

METHODS

Our system mainly consists of 2 deep learning modules: entity extraction and relation extraction. For each module, state-of-the-art deep learning models were applied. We trained and evaluated the models using 1040 in-house Japanese computed tomography (CT) reports annotated by medical experts. We also evaluated the performance of the entire pipeline of our system. In addition, the ratio of annotated entities in the reports was measured to validate the coverage of the clinical information with our information model.

RESULTS

The microaveraged F1-scores of our best-performing model for entity extraction and relation extraction were 96.1% and 97.4%, respectively. The microaveraged F1-score of the 2-stage system, which is a measure of the performance of the entire pipeline of our system, was 91.9%. Our system showed encouraging results for the conversion of free-text radiology reports into a structured format. The coverage of clinical information in the reports was 96.2% (6595/6853).

CONCLUSIONS

Our 2-stage deep system can extract clinical information from chest and abdomen CT reports accurately and comprehensively.

摘要

背景

放射学报告通常采用自由文本格式撰写,这使得报告的再利用具有挑战性。

目的

为了二次使用,我们开发了一个两阶段深度学习系统,用于提取临床信息并将其转换为结构化格式。

方法

我们的系统主要由两个深度学习模块组成:实体提取和关系提取。对于每个模块,应用了最先进的深度学习模型。我们使用由医学专家注释的1040份内部日本计算机断层扫描(CT)报告对模型进行训练和评估。我们还评估了系统整个流程的性能。此外,测量报告中注释实体的比例,以验证我们的信息模型对临床信息的覆盖范围。

结果

我们表现最佳的实体提取模型和关系提取模型的微平均F1分数分别为96.1%和97.4%。两阶段系统的微平均F1分数(衡量我们系统整个流程性能的指标)为91.9%。我们的系统在将自由文本放射学报告转换为结构化格式方面显示出令人鼓舞的结果。报告中临床信息的覆盖范围为96.2%(6595/6853)。

结论

我们的两阶段深度系统可以准确、全面地从胸部和腹部CT报告中提取临床信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b02/10686535/1385d917dc6c/medinform-v11-e49041-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b02/10686535/743abe0220dd/medinform-v11-e49041-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b02/10686535/89fa8d0018f8/medinform-v11-e49041-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b02/10686535/13ed2d93a3d4/medinform-v11-e49041-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b02/10686535/d523c7dfcfee/medinform-v11-e49041-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b02/10686535/6adf7a9b091d/medinform-v11-e49041-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b02/10686535/1385d917dc6c/medinform-v11-e49041-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b02/10686535/743abe0220dd/medinform-v11-e49041-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b02/10686535/89fa8d0018f8/medinform-v11-e49041-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b02/10686535/13ed2d93a3d4/medinform-v11-e49041-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b02/10686535/d523c7dfcfee/medinform-v11-e49041-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b02/10686535/6adf7a9b091d/medinform-v11-e49041-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b02/10686535/1385d917dc6c/medinform-v11-e49041-g006.jpg

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2
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JMIR Med Inform. 2020 Mar 31;8(3):e17984. doi: 10.2196/17984.
3
Extracting comprehensive clinical information for breast cancer using deep learning methods.利用深度学习方法提取乳腺癌全面临床信息。
通过增加训练数据量提高从日本药学服务记录中提取与医疗状况相关患者叙述的自然语言处理工具的性能:自然语言处理分析与验证研究
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Automated Detection of Cancer-Suspicious Findings in Japanese Radiology Reports with Natural Language Processing: A Multicenter Study.利用自然语言处理技术自动检测日本放射学报告中可疑癌症的发现:一项多中心研究。
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