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Adjuvant Osimertinib for Resected EGFR-Mutated Stage IB-IIIA Non-Small-Cell Lung Cancer: Updated Results From the Phase III Randomized ADAURA Trial.辅助奥希替尼治疗 EGFR 突变型 IB-IIIA 期非小细胞肺癌:III 期随机 ADAURA 试验的更新结果。
J Clin Oncol. 2023 Apr 1;41(10):1830-1840. doi: 10.1200/JCO.22.02186. Epub 2023 Jan 31.
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AENEAS: A Randomized Phase III Trial of Aumolertinib Versus Gefitinib as First-Line Therapy for Locally Advanced or MetastaticNon-Small-Cell Lung Cancer With Exon 19 Deletion or L858R Mutations.AENEAS:奥莫替尼对比吉非替尼一线治疗局部晚期或转移性非小细胞肺癌伴 exon19 缺失或 L858R 突变的随机 III 期研究。
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Efficacy and safety of adjuvant EGFR-TKIs for resected non-small cell lung cancer: a systematic review and meta-analysis based on randomized control trials.辅助 EGFR-TKIs 治疗可切除非小细胞肺癌的疗效和安全性:基于随机对照试验的系统评价和荟萃分析。
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ADAURA 能否做得更好?完善全球研究实践以减少癌症护理差距。

Could We Have Improved on ADAURA? Refining Global Research Practices to Reduce Cancer Care Disparities.

机构信息

Department of Medical Oncology, City of Hope Comprehensive Cancer Center, Duarte, CA.

AccessHope, Los Angeles, CA.

出版信息

JCO Glob Oncol. 2023 Sep;9:e2300344. doi: 10.1200/GO.23.00344.

DOI:10.1200/GO.23.00344
PMID:37992268
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10681540/
Abstract

ADAURA was a positive trial, but could changes have improved it and reduced global care disparities?

摘要

ADAURA 是一项阳性试验,但有没有可能通过改变来改善它并减少全球护理差距?