Kumar Hardik, Sharma Amit
Department of Pharmacy Practice, ISF College of Pharmacy, Moga, India.
Division of Neurology, Guru Gobind Singh Medical College and Hospital, Faridkot, India.
Int J Neurosci. 2024 Dec;134(12):1528-1540. doi: 10.1080/00207454.2023.2272042. Epub 2023 Nov 22.
The World Health Organization (WHO) defines quality of life as a person's assessment of their place in life in the context of the culture and value systems in which they live, as well as in connection to their objectives, expectations, standards, and worries. Physiological as well as emotional wellness both affect quality of life (QOL).
To assess and evaluate the quality of life in epileptic patients by using Quality of life in epilepsy inventory for adolescent (QOLIE-AD-48) and Quality of life in epilepsy inventory for adults (QOLIE-31) at tertiary care hospital.
After receiving approval from the Institution Ethics Committees (IEC) of the ISF College of Pharmacy and Guru Gobind Singh Medical College and Hospital, Faridkot. This observational and questionnaire based study was carried out for a period of six months. Quality of life in epilepsy inventory for adolescent (QOLIE-AD-48) and Quality of life in epilepsy inventory for adults (QOLIE-31) had been used for this research and got approval from Dr. Joyce A. Cramer to use the questionnaire.
Except for the patients who declined to participate in the study, 109 individuals who participated in the observation and questionnaire-based study was enrolled. In this study, it was discovered that adolescents made up the majority of the patients with respect to adults and quality of life was found to be good ( = 0.062). The mean score of quality of life of the patients and standard deviation () was found to be ( = 61.26) and ( = 21.10). Males (63%, 69 patients) were found higher with respect to females (37%, 40 patients). Linear regression test was found to be significant ( = 0.003) of quality of life score (dependent variable) in relation to age and weight (independent variable) of the patients it. One way ANOVA test was found significant of quality of life score in relation to educational status ( = 0.001), epilepsy from last year ( = 0.001), and drug therapy ( = 0.017).
The current study explains the relationship between quality of life and other dependent variables by using different statistical analysis techniques. The quality of life of epileptic patients must be assessed on an individual basis, taking into consideration the patient's state of physical health and psychological state. This study concludes that the quality of life of epileptic patients was found to be good as per significant results. If any of factors changes then there will also be differ in quality of life score.
世界卫生组织（WHO）将生活质量定义为一个人在其所处的文化和价值体系背景下，对自己在生活中所处位置的评估，以及与他们的目标、期望、标准和担忧的关联。生理健康和情绪健康都会影响生活质量（QOL）。
在三级护理医院，使用青少年癫痫生活质量量表（QOLIE - AD - 48）和成人癫痫生活质量量表（QOLIE - 31）评估和评价癫痫患者的生活质量。
在获得印度锡克教大学药学院、法里德科特古鲁·戈宾德·辛格医学院及医院的机构伦理委员会（IEC）批准后。这项基于观察和问卷调查的研究进行了六个月。本研究使用了青少年癫痫生活质量量表（QOLIE - AD - 48）和成人癫痫生活质量量表（QOLIE - 31），并获得了乔伊斯·A·克莱默博士使用该问卷的批准。
除拒绝参与研究的患者外，共有109名参与观察和问卷调查研究的个体被纳入。在本研究中，发现青少年患者在患者总数中占多数，且生活质量被发现良好（= 0.062）。患者生活质量的平均得分及标准差（）分别为（= 61.26）和（= 21.10）。男性（63%，69例）在数量上高于女性（37%，40例）。发现生活质量得分（因变量）与患者年龄和体重（自变量）的线性回归检验具有显著性（= 0.003）。单因素方差分析检验发现生活质量得分与教育程度（= 0.001）、癫痫患病年限（= 0.001）和药物治疗（= 0.017）有关。
本研究通过使用不同的统计分析技术解释了生活质量与其他相关变量之间的关系。必须根据个体情况评估癫痫患者的生活质量，同时考虑患者的身体健康状况和心理状态。本研究得出结论，根据显著结果，癫痫患者的生活质量良好。如果任何一个因素发生变化，生活质量得分也会有所不同。
