Department of Neurology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, Guangdong, China.
Department of Radiology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, Guangdong, China.
J Neuroimmunol. 2023 Dec 15;385:578223. doi: 10.1016/j.jneuroim.2023.578223. Epub 2023 Oct 24.
Hemiparesis is a frequently observed manifestation of stroke but exceptionally rare in the context of neuromyelitis optica spectrum disorder (NMOSD). In this case, a 68-year-old woman initially presented with acute right-sided weakness, leading to suspicion of ischemic stroke. However, her symptoms worsened despite treatment with aspirin and statins. Subsequent spinal MRI and aquaporin 4 antibody testing confirmed the diagnosis of NMOSD. The administration of methylprednisolone and immunoglobulin resulted in improved clinical outcomes. This case serves as an illustrative example of the diverse manifestations encountered in NMOSD and underscores the significance of considering this potential etiology in elderly patients to facilitate prompt diagnosis and therapeutic intervention.
偏瘫是中风的常见表现，但在视神经脊髓炎谱系障碍（NMOSD）的情况下极为罕见。本例为一位 68 岁女性，最初表现为右侧急性无力，疑似缺血性脑卒中。但尽管给予阿司匹林和他汀类药物治疗，其症状仍持续恶化。随后的脊髓 MRI 和水通道蛋白 4 抗体检测结果证实了 NMOSD 的诊断。给予甲基强的松龙和免疫球蛋白治疗后，临床结局得到改善。该病例说明 NMOSD 具有多种表现，对于老年患者，考虑到这种潜在病因，有助于及时诊断和治疗。
