Unraveling the Mechanisms Underlying Disordered Sleep in Alzheimer's Disease.
作者信息
Luke Russell, Alymova Irina
机构信息
Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario M5S 3G5, Canada
Collaborative Program in Neuroscience, University of Toronto, Toronto, Ontario M5S 3G5, Canada.
出版信息
J Neurosci. 2023 Nov 22;43(47):7899-7901. doi: 10.1523/JNEUROSCI.1440-23.2023.
Abstract
摘要
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本文引用的文献
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Effect of Aging and a Dual Orexin Receptor Antagonist on Sleep Architecture and Non-REM Oscillations Including an REM Behavior Disorder Phenotype in the PS19 Mouse Model of Tauopathy.衰老和双重食欲素受体拮抗剂对 Tauopathy 模型 PS19 小鼠睡眠结构和非快速动眼期振荡的影响，包括 REM 行为障碍表型。
J Neurosci. 2023 Jun 21;43(25):4738-4749. doi: 10.1523/JNEUROSCI.1828-22.2023. Epub 2023 May 25.
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Suvorexant Acutely Decreases Tau Phosphorylation and Aβ in the Human CNS.苏沃雷生可急性降低人中枢神经系统中的 Tau 磷酸化和 Aβ。
Ann Neurol. 2023 Jul;94(1):27-40. doi: 10.1002/ana.26641. Epub 2023 Apr 20.
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A noradrenergic-hypothalamic neural substrate for stress-induced sleep disturbances.应激引起睡眠障碍的去甲肾上腺素能-下丘脑神经基质。
Proc Natl Acad Sci U S A. 2022 Nov 8;119(45):e2123528119. doi: 10.1073/pnas.2123528119. Epub 2022 Nov 4.
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Propagated α-synucleinopathy recapitulates REM sleep behaviour disorder followed by parkinsonian phenotypes in mice.传播的 α-突触核蛋白病在小鼠中再现了 REM 睡眠行为障碍，随后出现帕金森病表型。
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Bidirectional relationship between sleep and Alzheimer's disease: role of amyloid, tau, and other factors.睡眠与阿尔茨海默病的双向关系：淀粉样蛋白、tau 及其他因素的作用。
Neuropsychopharmacology. 2020 Jan;45(1):104-120. doi: 10.1038/s41386-019-0478-5. Epub 2019 Aug 13.
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Chronic Sleep Disruption Advances the Temporal Progression of Tauopathy in P301S Mutant Mice.慢性睡眠中断会加速 P301S 突变小鼠 tau 病的时间进程。
J Neurosci. 2018 Nov 28;38(48):10255-10270. doi: 10.1523/JNEUROSCI.0275-18.2018. Epub 2018 Oct 15.
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Neurodegenerative disease status and post-mortem pathology in idiopathic rapid-eye-movement sleep behaviour disorder: an observational cohort study.特发性快速眼动睡眠行为障碍的神经退行性疾病状态和死后病理学：一项观察性队列研究。
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Electrophysiological changes precede morphological changes to frontal cortical pyramidal neurons in the rTg4510 mouse model of progressive tauopathy.电生理变化先于额皮质锥体神经元的形态变化，发生在 rTg4510 小鼠进行性 Tau 病模型中。
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