Jindal Tarun, Sarwal Ankush, Jain Prateek, Koju Rajan, Mukherjee Satyadip
Department of Uro-oncologyy, Tata Medical Centre, Kolkata, India.
Department of Uro-Oncology, NH Narayana Superspeciality Hospital, Howrah, India.
Curr Urol. 2023 Dec;17(4):257-261. doi: 10.1097/CU9.0000000000000160. Epub 2022 Sep 28.
Transurethral resection of bladder tumor (TURBT) is associated with perioperative morbidity of 5% to 10%, which can lead to unplanned readmissions. In this study, we aimed to identify the factors that lead to an increased risk of unplanned readmissions within 30 days of primary TURBT.
A retrospective study was conducted to identify patients who underwent primary TURBT at our institute from 2011 to 2019. Clinical and demographic factors, history of smoking, antiplatelet drugs intake, comorbidities, tumor size (<3 or >3 cm), multifocality, and histopathological type were abstracted. Patients who were readmitted were identified, and reasons for admission were recorded.
A total of 435 patients were identified. The median age of the patients was 66 years. From 378 male patients (86.9%), 110 (25.3%) and 37 (8.5%) had a history of smoking and antiplatelet agents intake, respectively. In the cohort, 166 patients (38.2%) were diabetic, 239 (54.9%) were hypertensive, 72 (16.6%) had chronic obstructive pulmonary disease, and 78 (7.9%) had hypothyroidism. A total of 206 patients (47.4%) had a tumor >3 cm; multifocality was seen in 140 (32.2%) patients, whereas muscle invasive tumors were present in 161 patients (37%). A total of 22 patients (5.06%) had readmissions within 30 days, with hematuria being the most common etiology. On univariate and multivariate analyses, a history of smoking ( = 0.006 and = 0.008, respectively) or antiplatelet agents intake ( < 0.001 and < 0.001, respectively) was significantly associated with increased unplanned readmission.
Our study revealed smoking and antiplatelet agents intake as factors leading to an increased risk of unplanned readmissions.
经尿道膀胱肿瘤切除术（TURBT）围手术期发病率为5%至10%，这可能导致非计划再次入院。在本研究中，我们旨在确定导致初次TURBT后30天内非计划再次入院风险增加的因素。
进行一项回顾性研究，以确定2011年至2019年在我院接受初次TURBT的患者。提取临床和人口统计学因素、吸烟史、抗血小板药物服用情况、合并症、肿瘤大小（<3或>3 cm）、多灶性及组织病理学类型。确定再次入院的患者，并记录入院原因。
共确定435例患者。患者的中位年龄为66岁。378例男性患者（86.9%）中，分别有110例（25.3%）和37例（8.5%）有吸烟史和抗血小板药物服用史。在该队列中，166例患者（38.2%）患有糖尿病，239例（54.9%）患有高血压，72例（16.6%）患有慢性阻塞性肺疾病，78例（7.9%）患有甲状腺功能减退症。共有206例患者（47.4%）肿瘤>3 cm；140例（32.2%）患者有多灶性，而161例患者（37%）存在肌层浸润性肿瘤。共有22例患者（5.06%）在30天内再次入院，血尿是最常见的病因。单因素和多因素分析显示，吸烟史（分别为=0.006和=0.008）或抗血小板药物服用史（分别为<0.001和<0.001）与非计划再次入院风险增加显著相关。
我们的研究表明，吸烟和服用抗血小板药物是导致非计划再次入院风险增加的因素。
