新冠疫情第二年在重症监护病房随访的新冠肺炎患者评估：一项多中心现患率研究
Evaluation of Patients with COVID-19 Followed Up in Intensive Care Units in the Second Year of the Pandemic: A Multicenter Point Prevalence Study.
作者信息
Güngör Sinem, Ediboğlu Özlem, Yazıcıoğlu Moçin Özlem, Adıgüzel Nalan, Tuncay Eylem, Ekiz İşcanlı İnşa Gül, Er Berrin, Karakurt Zuhal, Turan Sema, Kosovalı Behiye Deniz, Mutlu Nevzat Mehmet, Kayar Duygu, Gökbulut Bektaş Şerife, Uysal Elmas, Seğmen Fatih, Alp Gürayalp, Erdem Deniz, Has Selmi Nazan, Güven Pınar, Özçelik Zerrin, Ocakcıoğlu Merve, Yazıcı Özgür Canan, Yılmaz Rabia, Bilgi Özel Deniz, Cebeci Halil, Güler Bahar, Cansever Canan, Çakırca Mehmet, İnceöz Hansa, Solmaz İlker, Özkan Sipahioğlu Fatma, Aydın Eda Macit, Dayanır Hakan, Öner Sait Fatih, Karatepe Umut, Özen Serkan, Boran Maruf, Ergül Dursun Fırat, Kasapoğlu Umut Sabri, Delen Leman Acun, Toy Erol, Altun Koray, Albayrak Tuna, Yanal Hülya, Zaim Gizem, Yarar Volkan, Kılınç Gökhan, Deniz Mustafa, Özdemir Esra, Soylu Veysel Garani, Yılmaz Ayşe, Saygılı Saba Mukaddes, Öztürk Ejder Kamil, Ergan Begüm, Eyüpoğlu Selin, Şahin Yiğit, Yüksel Beyza, Bulut Azime, Sarıtaş Aykut, Yeniay Hicret, Genç Mürşide, Kargın Feyza, Özcan Osman, Karakoç Ebru, Karaca Ümran, Sözütek Didem, Sarı Sema, Şenoğlu Nimet, Aygün Hakan, Yiğit Arzu Ceren, Kavruk Nilgün, Uzan Çağdaş Alp, Bıçakcıoğlu Murat, Solak Serkan, Kutbay Özçelik Hatice, Uluç Kamuran, Yıldırım İlker, Arar Makbule Cavidan, Demirel İsmail, Küver Soner Umut, Özgür Eylem Sercan, Aydın Kutlay, Erdal Dönmez Gül, Aygencel Gülbin, Esmaoğlu Aliye, Sebil Aydın Berrak, Tokur Murat Emre, Korkmaz Ekren Pervin, Aydemir Yusuf, Çakır Güney Başak, Erdil Ömer Yavuz, Tünay Abdurrahman, Bahadır Türkan, Uçkun Serkan, Kocaoğlu Nazan, Pınar Hüseyin Ulaş, Kutluer Karaca Nurcan, Gültekin Hamza, Ayvat Pınar, Belin Özer Ayşe, Eroğlu Ahmet, Kuyrukluyıldız Ufuk, Baytar Çağdaş, Ayoğlu Hilal, Mızrakçı Serpil, Metin Hatice, Zanbak Mutlu Özgecan Pırıl, Yılmaz Hakan, Tüzüner Filiz
机构信息
Department of Respiratory Intensive Care, University of Health Sciences Süreyyapaşa Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, Turkey.
Department of Intensive Care Unit, University of Health Sciences İzmir Dr. Suat Şeren Chest Diseases and Thoracic Surgery Training and Research Hospital, İzmir, Turkey.
出版信息
Thorac Res Pract. 2023 Nov 22;25(1):11 - 16. doi: 10.5152/ThoracResPract.2023.23024.
OBJECTIVE
A 1-day point prevalence study was planned to obtain country data by determining the clinical characteristics, follow-up and treatment methods of coronavirus disease 2019 (COVID-19) cases that required intensive care unit (ICU) treatment in the second year of the pandemic.
MATERIAL AND METHODS
All patients who were hospitalized in the ICUs due to COVID-19 between March 11, 2022, 08.00 am, and March 12, 2022, 08.00 am, were included in the study. Demographic characteristics, intensive care and laboratory data, radiological characteristics, and follow-up results of the patients were recorded.
RESULTS
A total of 811 patients from 59 centers were included in the study, 59% of the cases were male, and the mean age was 74 ± 14 years. At least one comorbid disease was present in 94% of the cases, and hypertension was the most common. When ICU weight scores were examined, Acute Physiology and Chronic Health Evaluation-II: 19 (15-27) and Sequential Organ Failure Assessment: 7 (4-10) were seen. Sepsis was present in 37% (n = 298) of cases. PaO2/FiO2 ratios of the patients were 190 the highest and 150 the lowest and 51% of the cases were followed via invasive mechanical ventilation. On the study day, 73% bilateral involvement was seen on chest x-ray, and ground-glass opacities (52%) were the most common on chest tomography. There was growth in culture in 40% (n = 318) of the cases, and the most common growth was in the tracheal aspirate (42%).
CONCLUSION
The clinical course of COVID-19 is variable, and ICU follow-up was required due to advanced age, comorbidity, presence of respiratory symptoms, and widespread radiological involvement. The need for respiratory support and the presence of secondary infection are important issues to be considered in the follow-up. Despite the end of the second year of the pandemic and vaccination, the high severity of the disease as well as the need for follow-up in ICUs has shown that COVID-19 is an important health problem.COVID-19, intensive care, intensive care unit, pandemic, follow-up
目的
计划开展一项为期1天的现患率研究，通过确定大流行第二年需要重症监护病房（ICU）治疗的2019冠状病毒病（COVID-19）病例的临床特征、随访情况及治疗方法，来获取全国数据。
材料与方法
纳入2022年3月11日上午8点至2022年3月12日上午8点期间因COVID-19入住ICU的所有患者。记录患者的人口统计学特征、重症监护和实验室数据、放射学特征及随访结果。
结果
本研究共纳入来自59个中心的811例患者，59%的病例为男性，平均年龄为74±14岁。94%的病例至少有一种合并症，高血压最为常见。检查ICU病情严重程度评分时，急性生理与慢性健康状况评分系统II（APACHE-II）为19（15 - 27），序贯器官衰竭评估（SOFA）为7（4 - 10）。37%（n = 298）的病例存在脓毒症。患者的氧合指数（PaO2/FiO2）最高为190，最低为150，51%的病例接受有创机械通气治疗。在研究当天，胸部X光显示73%为双侧受累，胸部CT最常见的表现为磨玻璃影（52%）。40%（n = 318）的病例培养结果呈阳性，最常见的培养阳性部位是气管吸出物（42%）。
结论
COVID-19的临床病程具有变异性，由于患者年龄较大、存在合并症、有呼吸道症状以及广泛的放射学受累，需要在ICU进行随访。随访时需要考虑呼吸支持的需求以及继发感染的存在。尽管大流行已进入第二年且已开展疫苗接种，但该疾病的高严重性以及在ICU进行随访的必要性表明，COVID-19仍是一个重要的健康问题。COVID-19、重症监护、重症监护病房、大流行、随访
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