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唇腭裂患者行或不行成骨牵引的勒福Ⅰ型截骨术:圣何塞儿童医院的经验

Lefort I Osteotomy With and Without Osteogenic Distraction in Cleft Lip and Palate Patients: Experience at Hospital Universitario Infantil De San José.

作者信息

Prada Madrid Jose Rolando, Gómez Prada Diana Carolina, Gutierrez Rodríguez Erika Paola, Zarate Ardila Alisson, Pérez Quintero Juan Carlos

机构信息

Craniofacial Surgery Unit, Fundación Universitaria de Ciencias de la Salud (FUCS), Hospital Infantil Universitario de San José.

Fundación Universitaria de Ciencias de la Salud (FUCS), Hospital Infantil Universitario de San José, Center for Children With Cleft Lip and Palate (FISULAB).

出版信息

J Craniofac Surg. 2023 Nov 23. doi: 10.1097/SCS.0000000000009837.

DOI:10.1097/SCS.0000000000009837
PMID:37994847
Abstract

INTRODUCTION

Cleft lip and cleft palate (CLP) are congenital diseases that lead to several secondary craniofacial anomalies, such as hypoplasia of the middle third of the face, which can be treated with different surgical techniques to help improve functional and esthetic alterations associated with the maxilla. This article reports the results of patients managed with LeFort I osteotomy in the same craniofacial surgery center for 10 years.

OBJECTIVE

To determine the postoperative results regarding recurrence rates, malocclusion, and speech status after surgical treatment, in patients with retrusion of the midface with CLP, who underwent LeFort I osteotomy with or without osteogenic distraction (OD).

METHODS

A descriptive cohort study was performed at the Hospital Infantil Universitario de San José in Bogotá, Colombia, between 2010 and 2020, evaluating 38 patients with CLP who met the inclusion criteria, all managed by LeFort I osteotomy with and without OD. The authors reported the sociodemographic information, as well as data related to speech before and after surgery, recurrence, complications, and cephalometric characteristics. The recurrence of the patients was described at 6 and 12 months after the surgical procedure.

RESULTS

A total of 43 patients met the inclusion criteria, of which 20 patients were managed with conventional LeFort I osteotomy, and 23 with LeFort I osteotomy with OD; 5 patients were excluded due to lack of data in the medical records, with a final sample of 38 patients. The distribution based on sex was: 57.8% men and 42.1% women. Regarding laterality, we have 7 patients with right CLP (18.42%), 11 patients with left CLP (28.9%), and 20 patients with bilateral CLP (52.63%), 100% of patients with a class III bite in Angle's classification. In group 1 (OD), 55% of the patients did not present changes in speech before surgery, 30% presented improvement in speech, and 15% worsened it. In group 2 (conventional advancement), 66% of the patients did not present changes in speech, 5.5% presented improvement, and 27.7% presented worsening of speech based on the preoperative condition, with a clinical recurrence at 6 months of 15% for group 1 and of 33% for group 2, and at 1 year of 20% for group 1 and 16% for group 2.

CONCLUSIONS

Osteogenic distraction is a safe method that can be applied in patients with CLP depending on the clinical characteristics. According to what is described in the literature, those patients who require advancement of up to 6 mm treated without OD have obtained good results, showing esthetic improvement by increasing the projection of the middle third of the face, without worsening of velopharyngeal insufficiency and achieving an adequate occlusal class (Angle I) in the immediate postoperative period or after the postoperative orthodontic management. However, in patients who require advances ≥7 mm, it is clear that OD is the best option, given its association with a lower recurrence rate, minimal changes in the speech, achieving occlusion edge-to-edge at the end of the distraction or Angle's class I, which is corroborated by the results obtained in this study.

摘要

引言

唇腭裂(CLP)是一种先天性疾病,会导致多种继发性颅面畸形,如面部中三分之一发育不全,可通过不同的外科技术进行治疗,以帮助改善与上颌骨相关的功能和美观改变。本文报告了在同一颅面外科中心采用勒福Ⅰ型截骨术治疗10年的患者结果。

目的

确定接受或未接受牵张成骨术(OD)的勒福Ⅰ型截骨术治疗的CLP伴面中部后缩患者术后的复发率、错牙合及语音状况等结果。

方法

2010年至2020年在哥伦比亚波哥大的圣何塞大学儿童医院进行了一项描述性队列研究,评估38例符合纳入标准的CLP患者,均采用有或无OD的勒福Ⅰ型截骨术治疗。作者报告了社会人口统计学信息,以及术前和术后与语音、复发、并发症及头影测量特征相关的数据。在手术操作后6个月和12个月描述患者的复发情况。

结果

共有43例患者符合纳入标准,其中20例采用传统勒福Ⅰ型截骨术治疗,23例采用带OD的勒福Ⅰ型截骨术治疗;5例因病历数据缺失被排除,最终样本为38例患者。按性别分布为:男性57.8%,女性42.1%。关于侧别,我们有7例右侧CLP患者(18.42%),11例左侧CLP患者(28.9%),20例双侧CLP患者(52.63%),100%的患者在安氏分类中为Ⅲ类咬合。在第1组(OD)中,55%的患者术前语音无变化,30%的患者语音改善,15%的患者语音恶化。在第2组(传统前徙术)中,66%的患者语音无变化,5.5%的患者语音改善,27.7%的患者根据术前情况语音恶化,第1组6个月时临床复发率为15%,第2组为33%;1年时第1组为20%,第2组为16%。

结论

牵张成骨术是一种安全的方法,可根据临床特征应用于CLP患者。根据文献描述,那些需要前移达6mm且未行OD治疗的患者取得了良好效果,通过增加面部中三分之一的突出度显示出美观改善,未加重腭咽功能不全,且在术后即刻或术后正畸治疗后达到了合适的咬合分类(安氏Ⅰ类)。然而,对于需要前移≥7mm的患者,显然OD是最佳选择,因为其与较低的复发率、语音变化最小、在牵张结束时达到边缘对边缘咬合或安氏Ⅰ类相关,本研究所得结果证实了这一点。

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