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[动脉高血压与认知障碍。神经科医生的观点]

[Arterial hypertension and cognitive impairment. Neurologist's view].

作者信息

Fedin A I

机构信息

Pirogov Russian National Research Medical University, Moscow, Russia.

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 2023;123(11):7-13. doi: 10.17116/jnevro20231231117.

Abstract

The article presents a review of the literature on the relationship of cognitive impairment (CI) with arterial hypertension (AH). The pathogenetic mechanisms AH are characterized by the development of cerebral microangiopathy. Antihypertensive therapy (AHT) should take into account violations of autoregulation of cerebral blood flow in cerebrovascular disease and critical stenoses of large cerebral arteries, especially in fragile patients older than 80 years. The importance of AHT focused on the level of cerebral perfusion blood pressure, the severity of CI and the physical functioning of patients is emphasized. Neurocytoprotective therapy is recommended for correction of CI.

摘要

本文对认知障碍(CI)与动脉高血压(AH)之间关系的文献进行了综述。AH的发病机制以脑微血管病的发展为特征。抗高血压治疗(AHT)应考虑到脑血管疾病中脑血流自动调节功能的破坏以及大脑大动脉的严重狭窄,尤其是在80岁以上的脆弱患者中。强调了以脑灌注血压水平、CI严重程度和患者身体功能为重点的AHT的重要性。建议采用神经细胞保护疗法来纠正CI。

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