Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, TX, USA.
Department of Animal Science, Texas A&M University, College Station, TX, USA.
Results Probl Cell Differ. 2024;71:127-142. doi: 10.1007/978-3-031-37936-9_7.
Placentation is the development of a temporary arrangement between the maternal uterus and blastocyst-derived placental tissues designed to transport nutrients, gases, and other products from the mother to the embryo and fetus. Placentation differs histologically among species, but all types of placentation share the common trait of utilizing highly complex cell-to-cell and tissue-to-tissue morphological and biochemical interactions to remodel the uterine-placental interface. An elegant series of electron microscopy (EM) images supports the classification of ovine placentation as synepitheliochorial, because uterine luminal epithelial (LE) cells are maintained at the uterine-placental interface through incorporation into trophoblast syncytial plaques. In this review, we utilize immunofluorescence microscopy to provide further insights into early syncytialization of the ovine placenta. These observations, based on results using immunofluorescence microscopy, complement and expand, not replace, our understanding of syncytialization in sheep.
胎盘形成是母体子宫和胚泡衍生的胎盘组织之间暂时安排的发展，旨在将营养物质、气体和其他产物从母体输送到胚胎和胎儿。胎盘形成在物种间在组织学上有所不同，但所有类型的胎盘形成都有一个共同的特点，即利用高度复杂的细胞间和组织间形态和生化相互作用来重塑子宫胎盘界面。一系列优雅的电子显微镜 (EM) 图像支持将绵羊胎盘形成归类为上皮合胞体胎盘，因为子宫腔上皮 (LE) 细胞通过整合到滋养层合胞体斑块中而在子宫胎盘界面得以维持。在这篇综述中，我们利用免疫荧光显微镜进一步深入了解绵羊胎盘的早期合胞化。这些基于免疫荧光显微镜结果的观察结果补充和扩展了我们对绵羊合胞化的理解，而不是替代。
