Department of Obstetrics and Gynecology, Quan Zhou Women's and Children's Hospital, Quanzhou, China.
Department of Rehabilitation Medicine, Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou, China.
Acta Obstet Gynecol Scand. 2024 Feb;103(2):225-240. doi: 10.1111/aogs.14714. Epub 2023 Nov 23.
Lumbopelvic pain (LPP) is common in pregnant women and has a significant negative effect on physical and psychological health. In this study, for the first time, we conduct a meta-analysis to estimate the overall prevalence of LPP among pregnant women and clarify the reasons for the differences in the estimated results.
A systematic search of four databases (PubMed, Embase, Web of Science and Cochrane Central Register of Controlled Trials) was conducted from inception until October 2022. Two reviewers conducted a methodological quality assessment. Random-effects model analysis was used to estimate the pooled prevalence and the 95% confidence interval. Chi-square tests and I -values were used to assess the heterogeneity. Subgroup analysis (according to the participants' continent, age, body mass index [BMI], gestational age and study risk of bias), sensitivity analysis and random-effects meta-regression were used to explore the the sources of heterogeneity.
Of the 1661 unique citations, 38 studies (21 533 pregnant participants) were included in this systematic review and meta-analysis. The overall pooled prevalence of LPP during pregnancy was 63% (95% CI: 0.57 to 0.69), with significant heterogeneity (I = 99.1%, P < 0.001). The prevalence differed by participants' continents, 71% (North America), 74% (South America), 63% (Asia), 64% (Europe), 59% (Africa) and 45% (Oceania). The prevalence differed by BMI, 64% (BMI <25), 64% (25 ≤ BMI ≤ 28), and 71% (BMI >28). The prevalence differed by age, 72% (age <25 years), 58% (25 ≤ age ≤ 30 years), and 69% (age >30 years). The prevalence were the same differed by study risk of bias, 63% (both low and moderate risk of bias studies). The prevalence were similar by gestational age, 62% (second trimester) and 63% (third trimester).
Lumbopelvic pain during pregnancy is common; about three-fifths of pregnant women experience LPP. More prevention and intervention research for lumbopelvic should be conducted in pregnant women with different clinical characteristics.
腰骨盆疼痛(LPP)在孕妇中很常见,对身心健康有显著的负面影响。在这项研究中,我们首次进行了荟萃分析,以估计孕妇中 LPP 的总体患病率,并阐明导致估计结果差异的原因。
从成立到 2022 年 10 月,对四个数据库(PubMed、Embase、Web of Science 和 Cochrane 中央对照试验注册中心)进行了系统搜索。两名审查员进行了方法学质量评估。使用随机效应模型分析来估计合并患病率和 95%置信区间。使用卡方检验和 I 值来评估异质性。亚组分析(根据参与者的大陆、年龄、体重指数 [BMI]、妊娠年龄和研究偏倚风险)、敏感性分析和随机效应荟萃回归用于探索异质性的来源。
在 1661 条独特的引文,38 项研究(21533 名孕妇)被纳入这项系统综述和荟萃分析。怀孕期间 LPP 的总体合并患病率为 63%(95%CI:0.57 至 0.69),存在显著的异质性(I = 99.1%,P < 0.001)。患病率因参与者的大陆而异,71%(北美)、74%(南美)、63%(亚洲)、64%(欧洲)、59%(非洲)和 45%(大洋洲)。患病率因 BMI 而异,64%(BMI<25)、64%(25≤BMI≤28)和 71%(BMI>28)。患病率因年龄而异,72%(年龄<25 岁)、58%(25≤年龄≤30 岁)和 69%(年龄>30 岁)。患病率因研究偏倚风险而异,63%(低和中度偏倚风险研究)相同。患病率因妊娠年龄而异,62%(中期妊娠)和 63%(晚期妊娠)相似。
怀孕期间的腰骨盆疼痛很常见;大约五分之三的孕妇会经历 LPP。应针对不同临床特征的孕妇开展更多的腰骶部预防和干预研究。