Hsueh Fu-Sheng, Chen Hung-Chieh, Tzeng Huey-En
Department of Radiology, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Department of Radiology, Division of Neuroradiology, Taichung Veterans General Hospital, Taichung 40705, Taiwan.
Diagnostics (Basel). 2023 Nov 10;13(22):3424. doi: 10.3390/diagnostics13223424.
Central nervous system (CNS) involvement in diffuse large B-cell lymphoma (DLBCL) is relatively uncommon, occurring in approximately 5% of cases, with the majority of instances manifesting during relapse and often associated with poor prognoses. The aim of this case report is to present a unique occurrence of non-enhancing relapse of CNS lymphoma. Significantly, the patient had recently encountered a disease involvement in the axilla region, and subsequent to scheduled chemotherapy, she developed persistent neurological symptoms, leading to the discovery of a relapse of the CNS lymphoma. Our focus will be on delineating the clinical presentation, elucidating the findings observed in clinical imaging, and detailing the therapeutic approaches employed in this specific case. By highlighting these aspects, we aim to provide valuable insights into the diagnosis of the atypical presentation of CNS lymphoma.
中枢神经系统（CNS）受累于弥漫性大B细胞淋巴瘤（DLBCL）相对不常见，约5%的病例会出现，大多数情况发生在复发期间，且常与预后不良相关。本病例报告的目的是呈现中枢神经系统淋巴瘤非强化复发的独特病例。值得注意的是，该患者近期腋窝区域出现疾病累及，在预定化疗后，出现持续的神经症状，进而发现中枢神经系统淋巴瘤复发。我们将重点描述临床表现，阐明临床影像学观察结果，并详细说明该特定病例所采用的治疗方法。通过突出这些方面，我们旨在为中枢神经系统淋巴瘤非典型表现的诊断提供有价值的见解。
