使用PRECICE 2髓内钉延长先前接受过下肢巨大骨肿瘤重建治疗的患者肢体。

Lengthening Patients Previously Treated for Massive Lower Limb Reconstruction for Bone Tumors with the PRECICE 2 Nail.

作者信息

Campanacci Laura, Cevolani Luca, Focaccia Marco, Di Gennaro Giovanni Luigi, Dozza Barbara, Staals Eric, Zuccheri Federica, Bianchi Giuseppe, Donati Davide Maria, Manfrini Marco

机构信息

3rd Orthopaedic and Traumatologic Clinic Prevalently Oncologic, IRCCS Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136 Bologna, Italy.

Department of Pediatric Orthopedics and Traumatology, IRCCS Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136 Bologna, Italy.

出版信息

Children (Basel). 2023 Oct 31;10(11):1772. doi: 10.3390/children10111772.

DOI:10.3390/children10111772

PMID:38002863

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10670507/

Abstract

The objective of this study was to determine the efficacy of the PRECICE 2 nail in the treatment of lower limb length discrepancy in patients with a history of bone tumors. This study reports on outcomes, complications, and the safety of the PRECICE 2 limb lengthening nail in a cohort of pediatric patients with limb length discrepancy after surgery for bone tumors. Seventeen patients were treated with intramedullary magnetic nails. The average patient age at the time of surgery was 19 (range 11-32). The PRECICE 2 nail was used on 14 femurs (6 retrograde and 8 anterograde) and 3 tibias. The average consolidation time was 141 days (range 50-360) with a mean CI of 31 ± 12 days/cm. The ASAMI bone score showed 14 (82%) excellent results, 1 (6%) good result, and 2 (12%) poor results. The ASAMI functional score showed 13 (84.6%) excellent results, 3 (11.5%) good results, and 1 (3.8%) fair result. Patients treated with chemotherapy for bone cancer did not show any increase in distraction time or consolidation time. A total of 3 (17%) problems, 1 obstacle (5.5%), and 1 complication (5.5%) were encountered in our case series. The PRECICE 2 nail allows for effective and accurate lengthening preserving the range of motion in patients treated for bone tumors.

摘要

本研究的目的是确定PRECICE 2髓内钉治疗有骨肿瘤病史患者下肢长度不等的疗效。本研究报告了PRECICE 2肢体延长髓内钉在一组骨肿瘤手术后下肢长度不等的儿科患者中的治疗结果、并发症及安全性。17例患者接受了髓内磁性钉治疗。手术时患者的平均年龄为19岁（范围11 - 32岁）。PRECICE 2髓内钉应用于14个股骨（6例逆行和8例顺行）和3例胫骨。平均骨愈合时间为141天（范围50 - 360天），平均每厘米骨愈合时间的可信区间为31±12天。ASAMI骨评分显示，14例（82%）结果为优，1例（6%）结果为良，2例（12%）结果为差。ASAMI功能评分显示，13例（84.6%）结果为优，3例（11.5%）结果为良，1例（3.8%）结果为中。接受骨癌化疗的患者在延长时间或骨愈合时间上未出现任何增加。在我们的病例系列中，共出现3例（17%）问题、1例障碍（5.5%）和1例并发症（5.5%）。PRECICE 2髓内钉能够在骨肿瘤治疗患者中实现有效且精确的延长，并保留关节活动度。