• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

青少年恶性肿瘤切除术后使用电动延长髓内钉进行骨重建:初步结果

Bone reconstruction after malignant tumour resection using a motorized lengthening intramedullary nail in adolescents: preliminary results.

作者信息

Accadbled F, Thévenin Lemoine C, Poinsot E, Baron Trocellier T, Dauzere F, Sales de Gauzy J

机构信息

Department of Orthopaedics, Children's Hospital, CHU de Toulouse, France.

出版信息

J Child Orthop. 2019 Jun 1;13(3):324-329. doi: 10.1302/1863-2548.13.190016.

DOI:10.1302/1863-2548.13.190016
PMID:31312273
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6598045/
Abstract

PURPOSE

Bone reconstruction after malignant tumour of the lower limbs is a challenge. Our aim was to investigate the results of bone lengthening and transport using the Fitbone motorized lengthening nail.

METHODS

Eight patients were included. Two patients had had a tumour involving soft tissue only without bone resection. In six patients, the initial bone defect was 15.5 cm (8 to 24). The first step of reconstruction had consisted of temporary fixation and a cement spacer. The second step had consisted of bone grafting in five patients. One patient was managed with bone transport. Eventually, five patients had a limb-length discrepancy (LLD) managed with bone lengthening only. Two patients had a LLD and a nonunion managed with bone transport and lengthening. Mean age at bone lengthening was 15.2 years (11 to 19). Mean follow-up was 30.5 months (10 to 48).

RESULTS

In all, 11 nails were implanted in eight patients (eight femurs, three tibias). Mean length gain per procedure was 54.5 mm (30 to 80). Mean healing index was 48.4 days per cm (22.6 to 85.7). The complication rate was 18%. In two cases we observed a loose locking screw, which was revised. In all cases the lengthening involved the short bone (femur or tibia). Mean Musculoskeletal Tumor Society (MSTS) score improved from 52.7 (16.6 to 73.3) to 79.9 (63.3 to 96.6).

CONCLUSIONS

Bone reconstruction using a motorized intramedullary nail stands as a safe and reliable alternative after malignant tumour. It allows biological reconstruction with satisfactory clinical and radiological outcome and low complication rate.

LEVEL OF EVIDENCE

III.

摘要

目的

下肢恶性肿瘤后的骨重建是一项挑战。我们的目的是研究使用Fitbone电动延长钉进行骨延长和骨搬运的结果。

方法

纳入8例患者。2例患者仅软组织受累,未行骨切除。6例患者初始骨缺损为15.5 cm(8至24 cm)。重建的第一步包括临时固定和骨水泥间隔物。第二步,5例患者进行了骨移植。1例患者采用骨搬运治疗。最终,5例患者的肢体长度差异(LLD)仅通过骨延长进行处理。2例患者的LLD和骨不连采用骨搬运和延长治疗。骨延长时的平均年龄为15.2岁(11至19岁)。平均随访时间为30.5个月(10至48个月)。

结果

8例患者共植入11枚钉子(8例股骨,3例胫骨)。每次手术的平均长度增加为54.5 mm(30至80 mm)。平均愈合指数为每厘米48.4天(22.6至85.7天)。并发症发生率为18%。2例观察到锁定螺钉松动,进行了翻修。所有病例的延长均涉及短骨(股骨或胫骨)。肌肉骨骼肿瘤学会(MSTS)平均评分从52.7(16.6至73.3)提高到79.9(63.3至96.6)。

结论

使用电动髓内钉进行骨重建是恶性肿瘤后一种安全可靠的选择。它允许进行生物重建,临床和影像学结果令人满意,并发症发生率低。

证据水平

III级。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3230/6598045/84e47e9074ca/jco-13-324-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3230/6598045/84e47e9074ca/jco-13-324-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3230/6598045/84e47e9074ca/jco-13-324-g0001.jpg

相似文献

1
Bone reconstruction after malignant tumour resection using a motorized lengthening intramedullary nail in adolescents: preliminary results.青少年恶性肿瘤切除术后使用电动延长髓内钉进行骨重建:初步结果
J Child Orthop. 2019 Jun 1;13(3):324-329. doi: 10.1302/1863-2548.13.190016.
2
Bone lengthening using the Fitbone(®) motorized intramedullary nail: The first experience in France.使用 Fitbone(®)动力髓内钉进行骨延长:法国的首次经验。
Orthop Traumatol Surg Res. 2016 Apr;102(2):217-22. doi: 10.1016/j.otsr.2015.10.011. Epub 2016 Feb 10.
3
Bone Lengthening with a Motorized Intramedullary Nail in 34 Patients with Posttraumatic Limb Length Discrepancies.34例创伤后肢体长度差异患者采用动力型髓内钉进行骨延长术
J Clin Med. 2021 May 28;10(11):2393. doi: 10.3390/jcm10112393.
4
No osteolysis at the telescopic junction of 128 FITBONE lengthening nails.128 枚 FITBONE 延长钉的伸缩连接处无骨溶解。
Orthop Traumatol Surg Res. 2023 May;109(3):103501. doi: 10.1016/j.otsr.2022.103501. Epub 2022 Dec 5.
5
Lengthening in Congenital Femoral Deficiency: A Comparison of Circular External Fixation and a Motorized Intramedullary Nail.先天性股骨缺损的延长治疗:环形外固定与电动髓内钉的比较
J Bone Joint Surg Am. 2015 Sep 2;97(17):1432-40. doi: 10.2106/JBJS.N.00932.
6
Lower limb lengthening over an intramedullary nail: a long-term follow-up study of 28 cases.髓内钉延长下肢:28 例长期随访研究。
J Orthop Traumatol. 2019 Sep 10;20(1):30. doi: 10.1186/s10195-019-0538-y.
7
Lower limb lengthening and deformity correction using the Fitbone motorized nail system in the adolescent patient.在青少年患者中使用Fitbone电动髓内钉系统进行下肢延长和畸形矫正。
J Pediatr Orthop B. 2012 Mar;21(2):131-6. doi: 10.1097/BPB.0b013e32834b34b4.
8
Femoral Discrepancy After Childhood Bone Sarcoma Surgery Can Be Treated With Magnetic Intramedullary Nails.儿童骨肉瘤手术后的股骨长度差异可用磁性髓内钉治疗。
Orthopedics. 2023 Jan-Feb;46(1):27-34. doi: 10.3928/01477447-20221024-03. Epub 2022 Oct 28.
9
Complications in Elective Removal of 271 Bone Lengthening Nails (FITBONE, PRECICE and STRYDE).271枚骨延长钉(FITBONE、PRECICE和STRYDE)择期取出的并发症
Strategies Trauma Limb Reconstr. 2021 May-Aug;16(2):110-115. doi: 10.5005/jp-journals-10080-1529.
10
Intramedullary leg lengthening with a motorized nail.髓内钉动力延长术治疗下肢不等长。
Acta Orthop. 2011 Jun;82(3):344-50. doi: 10.3109/17453674.2011.584209. Epub 2011 May 11.

引用本文的文献

1
Lengthening Patients Previously Treated for Massive Lower Limb Reconstruction for Bone Tumors with the PRECICE 2 Nail.使用PRECICE 2髓内钉延长先前接受过下肢巨大骨肿瘤重建治疗的患者肢体。
Children (Basel). 2023 Oct 31;10(11):1772. doi: 10.3390/children10111772.
2
Plate-assisted bone-segment transport in the femur with 2 internal lengthening nails: a technical note and a case report.股骨 2 枚内置延长钉辅助骨段搬运:技术说明及病例报告。
Acta Orthop. 2023 Sep 13;94:466-470. doi: 10.2340/17453674.2023.18493.
3
Joint-preservation surgery for bone sarcoma in adolescents and young adults.

本文引用的文献

1
Two consecutive limb lengthenings with the same PRECICE nail: a technical note.使用同一根PRECICE髓内钉进行连续两次肢体延长:技术说明
Strategies Trauma Limb Reconstr. 2018 Nov;13(3):199-204. doi: 10.1007/s11751-018-0317-y. Epub 2018 Sep 19.
2
A-Frame free Vascularized Fibular Graft and Femoral Lengthening for Osteosarcoma Pediatric Patients.A形无框架带血管腓骨移植与股骨延长术治疗小儿骨肉瘤患者
J Pediatr Orthop. 2018 Feb;38(2):e83-e90. doi: 10.1097/BPO.0000000000000866.
3
Distraction osteogenesis reconstruction of large segmental bone defects after primary tumor resection: pitfalls and benefits.
青少年和年轻成人骨肉瘤的保关节手术
Int J Clin Oncol. 2023 Jan;28(1):12-27. doi: 10.1007/s10147-022-02154-4. Epub 2022 Mar 26.
4
Limb reconstruction in a resource-limited environment.资源有限环境下的肢体重建
SICOT J. 2021;7:66. doi: 10.1051/sicotj/2021066. Epub 2021 Dec 31.
5
A pH-response chemotherapy synergistic photothermal therapy for tumor suppression and bone regeneration by mussel-inspired Mg implant.一种受贻贝启发的镁植入物用于肿瘤抑制和骨再生的pH响应化疗协同光热疗法。
Regen Biomater. 2021 Sep 10;8(6):rbab053. doi: 10.1093/rb/rbab053. eCollection 2021 Oct.
6
Lower limb reconstruction for malignant bone tumours in children.儿童恶性骨肿瘤的下肢重建
J Child Orthop. 2021 Aug 20;15(4):346-357. doi: 10.1302/1863-2548.15.210126.
7
Complications common in motorized intramedullary bone transport for non-infected segmental defects: a retrospective review of 15 patients.动力化髓内骨搬运治疗非感染性节段性骨缺损常见并发症:15 例回顾性研究
Acta Orthop. 2021 Aug;92(4):485-492. doi: 10.1080/17453674.2021.1910777. Epub 2021 Jun 2.
8
Systematic review of complications with externally controlled motorized intramedullary bone lengthening nails (FITBONE and PRECICE) in 983 segments.体外控制式机动髓内骨延长钉(FITBONE 和 PRECICE)在 983 个部位的并发症的系统回顾。
Acta Orthop. 2021 Feb;92(1):120-127. doi: 10.1080/17453674.2020.1835321. Epub 2020 Oct 27.
原发性肿瘤切除术后大段骨缺损的牵张成骨重建:陷阱与益处
Eur J Orthop Surg Traumatol. 2017 Aug;27(6):715-727. doi: 10.1007/s00590-017-1998-5. Epub 2017 Jun 22.
4
Bone lengthening using the Fitbone(®) motorized intramedullary nail: The first experience in France.使用 Fitbone(®)动力髓内钉进行骨延长:法国的首次经验。
Orthop Traumatol Surg Res. 2016 Apr;102(2):217-22. doi: 10.1016/j.otsr.2015.10.011. Epub 2016 Feb 10.
5
Is the Induced-membrane Technique Successful for Limb Reconstruction After Resecting Large Bone Tumors in Children?诱导膜技术在儿童大骨肿瘤切除术后肢体重建中是否成功?
Clin Orthop Relat Res. 2015 Jun;473(6):2067-75. doi: 10.1007/s11999-015-4164-6. Epub 2015 Jan 30.
6
Bone transport of the tibia with a motorized intramedullary lengthening nail - a case report.使用电动髓内延长钉进行胫骨骨搬运——病例报告
Acta Orthop. 2014 Apr;85(2):211-3. doi: 10.3109/17453674.2014.887953. Epub 2014 Jan 30.
7
Bone tumor reconstruction with the Ilizarov method.骨肿瘤的伊利扎罗夫(Ilizarov)重建法。
J Surg Oncol. 2013 Mar;107(4):343-52. doi: 10.1002/jso.23217. Epub 2012 Jul 17.
8
Epiphysis preserving operations for the treatment of lower limb malignant bone tumors.保肢手术治疗下肢恶性骨肿瘤。
Eur J Surg Oncol. 2012 Dec;38(12):1165-70. doi: 10.1016/j.ejso.2012.05.005. Epub 2012 Jun 12.
9
Intercalary segmental reconstruction of long bones after malignant bone tumor resection using primary methyl methacrylate cement spacer interposition and secondary bone grafting: the induced membrane technique.使用甲基丙烯酸甲酯骨水泥间隔物原位植入及二期骨移植进行恶性骨肿瘤切除术后长骨节段间重建:诱导膜技术
J Pediatr Orthop. 2011 Jul-Aug;31(5):570-6. doi: 10.1097/BPO.0b013e31821ffa82.
10
Ewing's sarcoma.尤因氏肉瘤。
Lancet Oncol. 2010 Feb;11(2):184-92. doi: 10.1016/S1470-2045(09)70286-4.