Yue Lin, Lu Zengkui, Guo Tingting, Liu Jianbin, Yuan Chao, Yang Bohui
Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730050, China.
Sheep Breeding Engineering Technology Research Center of Chinese Academy of Agricultural Sciences, Lanzhou 730050, China.
Animals (Basel). 2023 Nov 17;13(22):3552. doi: 10.3390/ani13223552.
The gene encodes a secreted protein, and the gene is a member of the transcription factor family. Both genes have multiple biological functions. This study was conducted to investigate the association between and gene polymorphisms and wool fiber diameter and to determine potential molecular marker sites for breeding sheep with fine wool. We used Kompetitive Allele-Specific PCR to type the single nucleotide polymorphism (SNP) loci in the and genes within 1081 Alpine Merino sheep and associated these SNPs with wool fiber diameter. The results revealed one SNP in and , which were each related to sheep fiber diameter. The wool fiber diameters of sheep with the CC genotype in g.478807C>G and AA genotype in g.677G>A were the smallest and differed significantly from the diameters of other genotypes ( < 0.05). These results suggest potential molecular marker sites for fine-wool sheep breeding.
该基因编码一种分泌蛋白，且该基因是转录因子家族的成员。这两个基因都具有多种生物学功能。本研究旨在调查[未提及具体基因名称]基因多态性与羊毛纤维直径之间的关联，并确定用于培育细毛羊的潜在分子标记位点。我们使用竞争性等位基因特异性PCR对1081只高山美利奴羊的[未提及具体基因名称]基因中的单核苷酸多态性（SNP）位点进行分型，并将这些SNP与羊毛纤维直径相关联。结果在[未提及具体基因名称]中发现了一个SNP，且每个SNP都与绵羊纤维直径相关。在g.478807C>G位点具有CC基因型以及在g.677G>A位点具有AA基因型的绵羊的羊毛纤维直径最小，且与其他基因型的直径差异显著（P<0.05）。这些结果表明了细毛羊育种的潜在分子标记位点。
