[Optico-structural machine analysis of the nuclear chromatin and cytoplasmic SH-groups of epitheliocytes of the oral mucosa of healthy subjects and in peptic ulcer of the stomach and duodenum].

By means of optico-structural machine analysis, epitheliocytes of mucous membrane of the oral walls have been studied in 21 healthy persons and in 30 persons suffering from ulcerous disease of the stomach and duodenum. Changes in densitometric parameters of epitheliocytic nuclei at the ulcerous disease demonstrate increasing amount of heterochromatin and, hence, increasing degree of cell differentiation. Changes in contents and distribution of SH-groups in cell cytoplasm indicate that keratin is accumulated in it and that keratinization processes in the mucous membrane epithelium increase. In this way it is shown that the densitometric parameters are informative on distribution of hetero- and euchromatin in nuclei and SH-groups in epitheliocytic cytoplasm of the mucous membrane in the oral wall for estimation of morphofunctional state of these cells, normal and under pathological conditions.