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膳食蛋白质质量对暴露于模拟低压缺氧应激大鼠血清酶的影响。

Effect of dietary protein quality on the serum enzymes of rats exposed to simulated hypobaric hypoxic stress.

作者信息

Nikumb S K, Santhanam K, Rao M V

出版信息

Aviat Space Environ Med. 1986 Dec;57(12 Pt 1):1154-7.

PMID:3800815
Abstract

Changes in dietary protein quality and high altitude stress alter the serum urea cycle enzyme activities. To find a dietary protein which will facilitate quicker acclimatization to altitude stress, groups of rats were fed two diets, isocaloric and isonitrogenous, but differing in amino acid make up. The rats were exposed to simulated altitude stress of 0.5 atmospheric pressure for various periods up to 65 h. When serum arginase and ornithine transcarbamylase activities were assayed, it was seen that the group on the unbalanced protein (Cajanus cajan) diet showed less increase on exposure and a tendency to return to normal level earlier than the group on the balanced protein (egg) diet.

摘要

膳食蛋白质质量的变化和高原应激会改变血清尿素循环酶的活性。为了找到一种能促进更快适应高原应激的膳食蛋白质,将几组大鼠分别喂以两种等热量、等氮但氨基酸组成不同的日粮。将大鼠暴露于0.5个大气压的模拟高原应激环境中不同时长,最长达65小时。当检测血清精氨酸酶和鸟氨酸转氨甲酰酶的活性时,发现食用不均衡蛋白质(木豆)日粮的组在暴露后活性增加较少,且比食用均衡蛋白质(鸡蛋)日粮的组更早出现恢复到正常水平的趋势。

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