Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Oral and Maxillofacial Surgery, Augustenburger Platz 1, 13353 Berlin, Germany; Berlin Institute of Health (BIH), Anna-Louisa-Karsch-Straße 2, 10178 Berlin, Germany.
Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Oral and Maxillofacial Surgery, Augustenburger Platz 1, 13353 Berlin, Germany.
Br J Oral Maxillofac Surg. 2024 Jan;62(1):45-50. doi: 10.1016/j.bjoms.2023.10.012. Epub 2023 Oct 27.
Impaired bony healing following bilateral sagittal split osteotomy (BSSO) is a major unmet medical need for affected patients, and rare occurrences can hinder the identification of underlying risk factors. We hypothesised that osseous union following BSSO can be quantified using volumetric analysis, and we aimed to identify the risk factors for impaired bone healing. The percentage change in bony volume was measured in orthognathic patients following BSSO using two consecutive postoperative cone-beam computed tomography scans. Patients' characteristics and treatment parameters were documented, and correlation and regression analyses of these variables performed. Thirty-six patients (23 men and 13 women) with a mean (SD) age of 33.28 (11.86) years were included. The gap site (lingual versus buccal) (p < 0.01) had a significant impact on the change in volume. Age (p = 0.06) showed a trend towards significance. Initial width of the osteotomy gap, sex, and indication for surgery did not influence osseous healing. Increased age at surgery and the side of the buccal osteotomy are independent risk factors for impaired osseous healing following BSSO.
双侧矢状劈开截骨术（BSSO）后骨愈合受损是受影响患者的一个主要未满足的医疗需求，罕见的情况可能会阻碍对潜在风险因素的识别。我们假设可以使用体积分析来量化 BSSO 后的骨愈合情况，并旨在确定骨愈合受损的风险因素。使用两次连续的术后锥形束 CT 扫描，在正颌患者中测量 BSSO 后骨体积的百分比变化。记录患者的特征和治疗参数，并对这些变量进行相关性和回归分析。36 名患者（23 名男性和 13 名女性）的平均（SD）年龄为 33.28（11.86）岁。间隙部位（舌侧与颊侧）（p<0.01）对体积变化有显著影响。年龄（p=0.06）显示出有意义的趋势。初始骨切开间隙宽度、性别和手术指征均不影响骨愈合。手术时年龄增加和颊侧骨切开术侧是 BSSO 后骨愈合受损的独立危险因素。
