蛋白质修饰反应的动力学。催化功能所必需的酶蛋白基团的分数浓度或基团反应性的测定。
Kinetics of protein-modification reactions. Determination of the fractional concentration of enzyme protein groups, or group reactivities, essential for catalytic function.
作者信息
Rakitzis E T, Malliopoulou T B
出版信息
Biochem J. 1986 Jul 15;237(2):589-91. doi: 10.1042/bj2370589.
Abstract
A mathematical treatment of modification-induced enzyme protein inactivation is presented, and it is shown that, at initial reaction conditions, the ratio of the first derivative of the equation describing enzyme activity loss to the first derivative of the equation describing protein groups modification is equal to the fractional concentration of enzyme protein reactive groups, or group reactivities, essential for catalytic function.
摘要
本文给出了修饰诱导的酶蛋白失活的数学处理方法，结果表明，在初始反应条件下，描述酶活性丧失的方程的一阶导数与描述蛋白质基团修饰的方程的一阶导数之比，等于对催化功能至关重要的酶蛋白反应性基团的分数浓度，即基团反应性。
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Kinetics of protein-modification reactions. Determination of the fractional concentration of enzyme protein groups, or group reactivities, essential for catalytic function.蛋白质修饰反应的动力学。催化功能所必需的酶蛋白基团的分数浓度或基团反应性的测定。
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Kinetics of protein modification reactions. Plot of fractional enzyme activity versus extent of protein modification in cases where all modifiable groups are essential for enzyme activity.蛋白质修饰反应动力学。在所有可修饰基团对酶活性均至关重要的情况下，酶活性分数与蛋白质修饰程度的关系图。
Biochem J. 1984 Oct 1;223(1):259-62. doi: 10.1042/bj2230259.
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Kinetics of protein modification reactions.蛋白质修饰反应的动力学
Biochem J. 1984 Jan 15;217(2):341-51. doi: 10.1042/bj2170341.
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