脂肪组织中的脂肪合成。化学计量学限制的研究。
Fat synthesis in adipose tissue. An examination of stoichiometric constraints.
作者信息
Fell D A, Small J R
出版信息
Biochem J. 1986 Sep 15;238(3):781-6. doi: 10.1042/bj2380781.
Abstract
The requirement for net balance of synthesis, degradation and transport for all intermediates in the pathways from glucose to fat imposes constraints on the balance of fluxes between different pathways. Linear programming has been used to examine the interactions between these constraints on metabolism in adipocytes and the requirement for efficiency in the conversion of glucose into fat. The circumstances under which excessive ATP synthesis would accompany this conversion have been investigated.
摘要
从葡萄糖到脂肪的代谢途径中，所有中间产物的合成、降解和转运的净平衡要求，对不同途径之间的通量平衡施加了限制。线性规划已被用于研究这些对脂肪细胞代谢的限制因素之间的相互作用，以及葡萄糖转化为脂肪过程中对效率的要求。已经研究了在这种转化过程中伴随过量ATP合成的情况。
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