McIntire W S, Stults J T
Biochem Biophys Res Commun. 1986 Dec 15;141(2):562-8. doi: 10.1016/s0006-291x(86)80210-8.
Short amino acid sequences around the two linkage sites of the cofactor of methylamine dehydrogenase are presented. Mass spectral data indicates that the covalently bound cofactor is the tricyclic pyrroloquinoline quinone (PQQ). However, the 3 carboxyl groups characteristic of this o-quinone are absent. A cysteine thioether, via a methylene bridge, and a serine ether link the cofactor to the small subunit of methylamine dehydrogenase.
本文给出了甲胺脱氢酶辅因子两个连接位点周围的短氨基酸序列。质谱数据表明，共价结合的辅因子是三环吡咯并喹啉醌（PQQ）。然而，这种邻醌特有的3个羧基并不存在。一个半胱氨酸硫醚通过一个亚甲基桥，以及一个丝氨酸醚将辅因子与甲胺脱氢酶的小亚基相连。
