Rheumatology Department.
Radiotherapy and Oncology Department, CHU Orleans, Orleans, France.
Clin Nucl Med. 2024 Jan 1;49(1):74-75. doi: 10.1097/RLU.0000000000004969. Epub 2023 Nov 24.
PSMA-targeted PET agents are mainly involved for prostate cancer; however, unspecific bone uptakes can be challenging for the clinician. We report the case of a 71-year-old man with history of recurrent prostate cancer initially treated by surgery and radiation therapy. 18 F-PSMA 1007 PET/CT was performed. Beside hyperfixing lymph nodes, focal uptake was found in right femoral head with shell subchondral hypofixation and no morphologic correlate on CT. MRI found bilateral osteonecrosis of the femoral head. This case emphasizes that osteonecrosis of the femoral head can mimic a metastasis uptake, even with normal CT, without however the fixation being constant.
PSMA 靶向 PET 剂主要用于前列腺癌；然而，非特异性的骨摄取对临床医生来说具有挑战性。我们报告了一例 71 岁男性的病例，该患者患有复发性前列腺癌，最初接受了手术和放射治疗。进行了 18 F-PSMA 1007 PET/CT 检查。除了淋巴结高摄取外，还发现右侧股骨头有局灶性摄取，伴有软骨下壳骨低摄取，CT 无形态学相关性。MRI 发现双侧股骨头坏死。本例强调，即使 CT 正常，股骨头坏死也可以模拟转移摄取，而固定性不变。
