[大鼠大脑中的行为类型与超氧化物歧化酶活性（两种特赖恩品系的比较）]

[Type of behavior and superoxide dismutase activity in the brain of rats (a comparison of 2 Tryon strains)].

作者信息

Khonicheva N M, Guliaeva N V, Zhdanova I V, Obidin A B, Dmitrieva I L

出版信息

Biull Eksp Biol Med. 1986 Dec;102(12):643-5.

Abstract

Differences in the type of behaviour in capable ("maze-bright") and incapable ("maze-dull") Tryon rats have been demonstrated in the situation with pain-irritated partner by the method of "emotional resonance". Most "bright" rats belonged to the type not avoiding the signals of another pain-irritated rat, they revealed a persistent ecologically defensive reaction of preferring a small closed space. The type of anxiety behaviour prevailed in the group of "dull" rats. In the open field test "bright" rats were characterized by low locomotor activity and high level of defecation and "dull" rats by high activity and low defecation. Increased levels of superoxide dismutase activity and high content of thiobarbituric acid-reactive material were observed in brains of dull rats. The interrelations between behavioural and molecular levels of defensive response to stress is discussed.

摘要

通过“情感共鸣”方法，在有疼痛刺激伙伴的情境中，已证明有能力的（“迷宫聪明型”）和无能力的（“迷宫迟钝型”）特赖恩大鼠在行为类型上存在差异。大多数“聪明”大鼠属于不回避另一只疼痛刺激大鼠信号的类型，它们表现出持续的生态防御反应，更喜欢小的封闭空间。“迟钝”大鼠组中焦虑行为类型占主导。在旷场试验中，“聪明”大鼠的特征是运动活动低、排便水平高，而“迟钝”大鼠则是活动高、排便低。在“迟钝”大鼠的大脑中观察到超氧化物歧化酶活性水平升高和硫代巴比妥酸反应性物质含量高。讨论了对应激防御反应的行为和分子水平之间的相互关系。