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应对艾滋病病毒诊断延迟:新冠疫情时代的英国经验教训。

Tackling late HIV diagnosis: Lessons from the UK in the COVID-19 era.

机构信息

The Northern Contraception, Sexual Health and HIV Service, Manchester Royal Infirmary, Manchester, UK.

Chelsea and Westminster Hospital, London, UK.

出版信息

Int J STD AIDS. 2024 Mar;35(4):244-253. doi: 10.1177/09564624231202287. Epub 2023 Nov 28.

DOI:10.1177/09564624231202287
PMID:38016099
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10908195/
Abstract

INTRODUCTION

Late diagnosis of HIV is associated with increased morbidity and mortality, and an increased risk of non-infectious comorbidities. On a societal level, late diagnosis leads to higher treatment and healthcare costs and is a major driver of HIV transmission. Despite improvements in other areas of the HIV care pathway, late diagnosis remains an individual and public health concern globally.

OBJECTIVE

To examine the barriers to HIV testing and highlight successful strategies to improve prompt diagnosis. This review describes the prevalence of late diagnosis in the UK and discusses key factors that contribute to late diagnosis, including the effect of the COVID-19 pandemic. Late HIV diagnosis is lower in the UK than in most other European countries. In this review, pilot projects and ongoing initiatives that have reduced late diagnosis in the UK are highlighted; moreover, further strategies for improving prompt diagnosis are suggested.

CONCLUSIONS

Insufficient testing is the fundamental reason for late HIV diagnosis, with societal, systemic, and individual factors all contributing to inadequate testing. Improving access to testing, removing barriers to health-seeking behaviour, and ensuring all people with HIV indicator conditions are promptly tested are key to reducing the rates of late diagnosis globally.

摘要

引言

HIV 诊断较晚与发病率和死亡率增加以及非传染性合并症风险增加有关。从社会层面来看,诊断较晚会导致治疗和医疗保健费用增加,是 HIV 传播的主要驱动因素。尽管 HIV 护理途径的其他方面有所改善,但全球仍存在诊断较晚的问题,这是一个个人和公共卫生问题。

目的

探讨 HIV 检测的障碍,并强调改善及时诊断的成功策略。本综述描述了英国 HIV 诊断较晚的流行情况,并讨论了导致诊断较晚的关键因素,包括 COVID-19 大流行的影响。与大多数其他欧洲国家相比,英国的 HIV 诊断较晚的情况较少。在本综述中,强调了英国减少 HIV 诊断较晚的试点项目和正在进行的举措;此外,还提出了进一步改善及时诊断的策略。

结论

检测不足是 HIV 诊断较晚的根本原因,社会、系统和个人因素都导致检测不足。改善检测机会,消除寻求医疗保健行为的障碍,并确保所有 HIV 指征性疾病患者都能及时接受检测,是全球降低诊断较晚率的关键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f041/10908195/b73ad490a034/10.1177_09564624231202287-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f041/10908195/1c339c34a6eb/10.1177_09564624231202287-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f041/10908195/0dac782bc69c/10.1177_09564624231202287-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f041/10908195/b73ad490a034/10.1177_09564624231202287-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f041/10908195/1c339c34a6eb/10.1177_09564624231202287-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f041/10908195/0dac782bc69c/10.1177_09564624231202287-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f041/10908195/b73ad490a034/10.1177_09564624231202287-fig3.jpg

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Biomedicines. 2024 Aug 14;12(8):1846. doi: 10.3390/biomedicines12081846.
BMJ. 2022 Dec 12;379:o2989. doi: 10.1136/bmj.o2989.
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