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捷克共和国境内乌克兰难民中艾滋病毒的晚期诊断:一项回顾性观察研究。

Late diagnosis of HIV among Ukrainian refugees in the Czech Republic: A retrospective, observational study.

作者信息

Bartovská Zofia, Massmann Ricardo, Jilich David, Groh Tomáš, Fleischhans Lukáš, Zlámal Milan, Svačinka Radek, Vydrář David, Sedláček Dalibor, Kubiska Miroslav, Kapla Jaroslav, Nepovímová Lucie, Bartková Daniela, Olbrechtová Lenka, Jerhotová Zdeňka, Novotná Eva, Wnuk Jakub, Němeček Vratislav, Dlouhý Pavel, Cimrman Štěpán, Malý Marek

机构信息

Department of Infectious Diseases, 1st Faculty of Medicine, Charles University and Military University Hospital Prague, Prague, Czech Republic.

HIV/AIDS Centre, Clinic of Infectious Diseases Akademika Ladislava D'erera, University Hospital Bratislava, Bratislava, Slovakia.

出版信息

HIV Med. 2025 Jun;26(6):888-898. doi: 10.1111/hiv.70021. Epub 2025 Mar 29.

Abstract

OBJECTIVES

This retrospective, observational, non-interventional study describes the demographics, characteristics, immunological and virological status, coinfections, healthcare unit of HIV diagnosis and follow-up status of Ukrainian refugees with newly diagnosed HIV in the Czech Republic, with a special focus on those with a late HIV diagnosis.

METHODS

Ukrainian nationals with war refugee status, Ukrainian nationals with Czech Republic resident status and Czech Republic nationals who newly registered at HIV centres in the Czech Republic between March 2022 and June 2023 with a new diagnosis of HIV were included. Data were collected from medical records. The study was registered with the Czech State Institute for Drug Control (ID 2401240000).

RESULTS

In total, 298 patients with a new HIV diagnosis were included in the study. Of these, 58 patients were Ukrainian refugees who were retained in care. This cohort had a mean age of 37.0 years (min-max 13-60) and most (62.1%) were women. More than half of the Ukrainian refugees in this study (60.3%) had a late HIV diagnosis; these patients were older than those with a prompt diagnosis (mean age 40.7 vs. 31.5 years, p < 0.001). Ukrainian refugees were infrequently diagnosed in primary care and significantly more likely to have a late HIV diagnosis (60.3% vs. 37.8%, p = 0.005) and be diagnosed at a later HIV stage (p = 0.021) than Czech nationals.

CONCLUSION

Ukrainian refugees were more likely to have a late HIV diagnosis than Czech nationals.

摘要

目的

这项回顾性、观察性、非干预性研究描述了在捷克共和国新诊断出感染艾滋病毒的乌克兰难民的人口统计学特征、特点、免疫和病毒学状况、合并感染情况、艾滋病毒诊断的医疗机构以及随访状况,特别关注那些艾滋病毒诊断较晚的难民。

方法

纳入2022年3月至2023年6月期间在捷克共和国艾滋病毒中心新登记且新诊断出感染艾滋病毒的具有战争难民身份的乌克兰国民、具有捷克共和国居民身份的乌克兰国民以及捷克共和国国民。数据从医疗记录中收集。该研究已在捷克国家药物管制研究所注册(编号2401240000)。

结果

本研究共纳入298例新诊断出感染艾滋病毒的患者。其中,58例为接受护理的乌克兰难民。这一队列的平均年龄为37.0岁(最小 - 最大年龄13 - 60岁),大多数(62.1%)为女性。本研究中超过一半的乌克兰难民(60.3%)艾滋病毒诊断较晚;这些患者比诊断及时的患者年龄更大(平均年龄40.7岁对31.5岁,p < 0.001)。乌克兰难民在初级保健中很少被诊断出来,与捷克国民相比,他们艾滋病毒诊断较晚(60.3%对37.8%,p = 0.005)以及在艾滋病毒较晚阶段被诊断出来的可能性显著更高(p = 0.021)。

结论

与捷克国民相比,乌克兰难民艾滋病毒诊断较晚的可能性更大。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51fa/12127235/6747cfa601eb/HIV-26-888-g001.jpg

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