Acharya's NR Institute of Physiotherapy, Acharya Institute, Bengaluru, Karnataka, India.
Department of Physiotherapy, Center for Diabetic Foot Care and Research, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, India.
J Phys Act Health. 2023 Nov 28;21(2):164-170. doi: 10.1123/jpah.2023-0486. Print 2024 Feb 1.
Physical activity of any amount results in substantial health benefits. However, public awareness of physical activity benefits in chronic diseases is inadequate in India. Prediabetes is a significant health issue on a global scale. Visceral fat (VF) is considered as an early predictor of prediabetes. Ethnicity and race have a substantial impact on VF. Hence, this study intended to evaluate the effect of a customized physical activity promotion program on VF and glycemic parameters in individuals with prediabetes.
In the current, parallel group randomized controlled trial, a total of 158 participants were recruited: 79 in intervention and 79 in control group. The study included the prediabetes individuals based on American Diabetes Association criteria. Participants from the intervention group received the customized physical activity promotion program for 24 weeks. The primary outcome measures of the study were VF level and glycemic parameters that included fasting blood sugar and glycosylated hemoglobin. Two-way mixed analysis of variance was used to study the mean difference of an outcome between 2 groups over time.
The study found a statistically significant interaction between the intervention and times on VF level, F1,136 = 23.564, fasting blood sugar levels, F1,136 = 8.762, and glycosylated hemoglobin levels, F1,136 = 64.582 at the end of 24 weeks (P < .05).
This study concluded that a customized physical activity promotion program was effective in reducing VF in individuals with prediabetes as compared with controls. It improved glycemic control by reducing fasting blood sugar and glycosylated hemoglobin levels.
任何数量的身体活动都会带来显著的健康益处。然而，在印度，公众对身体活动对慢性病益处的认识不足。糖尿病前期是一个全球性的重大健康问题。内脏脂肪（VF）被认为是糖尿病前期的早期预测指标。种族和民族对 VF 有重大影响。因此，本研究旨在评估针对糖尿病前期个体的定制身体活动促进计划对 VF 和血糖参数的影响。
在当前的平行组随机对照试验中，共招募了 158 名参与者：干预组 79 名，对照组 79 名。研究纳入了符合美国糖尿病协会标准的糖尿病前期个体。干预组的参与者接受了为期 24 周的定制身体活动促进计划。研究的主要结局指标是 VF 水平和血糖参数，包括空腹血糖和糖化血红蛋白。采用双向混合方差分析研究 2 组之间在不同时间点的结局平均值差异。
研究发现，干预与时间对 VF 水平、F1,136 = 23.564、空腹血糖水平、F1,136 = 8.762 和糖化血红蛋白水平、F1,136 = 64.582 的交互作用具有统计学意义，24 周结束时（P <.05）。
本研究得出结论，与对照组相比，定制的身体活动促进计划可有效降低糖尿病前期个体的 VF。它通过降低空腹血糖和糖化血红蛋白水平来改善血糖控制。
