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心血管疾病风险的性别差异:从青春期到成年早期。

Gender differences in cardiovascular disease risk: Adolescence to young adulthood.

机构信息

School of Public Health, Faculty of Medicine, The University of Queensland, 266 Herston Road, Herston, Qld 4006, Australia.

Faculty of Medicine, The University of Queensland, Princess Alexandra Hospital, Woolloongabba, Qld 4102, Australia.

出版信息

Nutr Metab Cardiovasc Dis. 2024 Jan;34(1):98-106. doi: 10.1016/j.numecd.2023.09.024. Epub 2023 Sep 29.

Abstract

BACKGROUND AND AIMS

Gender differences in cardiovascular disease (CVD) have been well documented but rarely for young adults and the extent to which gender related lifestyle differences may contribute to gender differences in CVD risk experienced by young adults have not been reported.

METHODS AND RESULTS

Data are from a long-running cohort study, the Mater-University of Queensland Study of Pregnancy (MUSP). We track gender differences in CVD related behaviours at 21 and 30 years (consumption of a Western Diet/Health-Oriented Diet, cigarette smoking, vigorous physical exercise, heavy alcohol consumption). At 30 years we compare males and females for CVD risk, and the extent to which lifestyle behaviours at 21 and 30 years contribute to CVD risk. At both 21 and 30 years of age, males more frequently consume a Western Diet and less often a Health Oriented Diet. By contrast, males are also much more likely to report engaging in vigorous physical activity. On most CVD markers, males exhibit much higher levels of risk than do females at both 21 and 30 years. At 30 years of age males have about five times the odds of being at high risk of CVD. Some lifestyle behaviours contribute to this additional risk.

CONCLUSION

Young adult males much more frequently engage in most CVD related risk behaviours and males have a higher level of CVD risk. Gender differences in CVD risk remain high even after adjustment for CVD lifestyles, though dietary factors independently contribute to CVD risk at 30 years.

摘要

背景与目的

心血管疾病(CVD)的性别差异已有大量记载,但针对年轻人的此类差异却鲜见报道,且导致年轻人 CVD 风险存在性别差异的生活方式差异在何种程度上与性别相关也尚未可知。

方法与结果

数据来自一项长期队列研究,即 Mater-昆士兰大学妊娠研究(MUSP)。我们在 21 岁和 30 岁时跟踪与 CVD 相关的行为方面的性别差异(西式饮食/健康饮食的摄入、吸烟、剧烈身体活动、大量饮酒)。在 30 岁时,我们比较了男性和女性的 CVD 风险,以及 21 岁和 30 岁的生活方式行为对 CVD 风险的影响程度。在 21 岁和 30 岁时,男性更频繁地摄入西式饮食,而较少摄入健康饮食。相比之下,男性也更有可能报告进行剧烈的身体活动。在大多数 CVD 标志物上,男性在 21 岁和 30 岁时的风险水平均高于女性。在 30 岁时,男性患 CVD 的风险是女性的五倍左右。一些生活方式行为导致了这种额外的风险。

结论

年轻男性更频繁地从事大多数与 CVD 相关的风险行为,且男性的 CVD 风险水平更高。即使调整了 CVD 生活方式,CVD 风险的性别差异仍然很高,尽管饮食因素在 30 岁时独立导致 CVD 风险增加。

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