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3D 与 2D 模拟羊膜腔镜术治疗脊柱裂:一项定量运动分析。

3D vs. 2D simulated fetoscopy for spina bifida repair: a quantitative motion analysis.

机构信息

Department of Mechanical Engineering Sciences, Catholic University of Leuven, 3000, Leuven, Belgium.

Obstetrics and Gynaecology, University Hospital of Leuven, 3000, Leuven, Belgium.

出版信息

Sci Rep. 2023 Nov 28;13(1):20951. doi: 10.1038/s41598-023-47531-9.

DOI:10.1038/s41598-023-47531-9
PMID:38016964
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10684542/
Abstract

3D imaging technology is becoming more prominent every day. However, more validation is needed to understand the actual benefit of 3D versus conventional 2D vision. This work quantitatively investigates whether experts benefit from 3D vision during minimally invasive fetoscopic spina bifida (fSB) repair. A superiority study was designed involving one expert team ([Formula: see text] procedures prior) who performed six 2D and six 3D fSB repair simulations in a high-fidelity animal training model, using 3-port access. The 6D motion of the instruments was recorded. Among the motion metrics are total path length, smoothness, maximum speed, the modified Spectral Arc Length (SPARC), and Log Dimensionless Jerk (LDLJ). The primary clinical outcome is operation time (power 90%, 5% significance) using Sealed Envelope Ltd. 2012. Secondary clinical outcomes are water tightness of the repair, CO[Formula: see text] insufflation volume, and OSATS score. Findings show that total path length and LDLJ are considerably different. Operation time during 3D vision was found to be significantly shorter compared to 2D vision ([Formula: see text] vs. [Formula: see text] min; p [Formula: see text] 0.026). These results suggest enhanced performance with 3D vision during interrupted suturing in fetoscopic SBA repair. To confirm these results, a larger-scale follow-up study involving multiple experts and novice surgeons is recommended.

摘要

3D 成像技术日益突出。然而,需要更多的验证来了解 3D 与传统 2D 视觉的实际优势。本工作定量研究了专家在微创胎儿镜脊柱裂(fSB)修复中是否受益于 3D 视觉。一项优越性研究设计涉及一个专家团队([Formula: see text] 例前),他们在高保真动物培训模型中使用 3 端口通道进行了 6 例 2D 和 6 例 3D fSB 修复模拟。记录仪器的 6D 运动。运动指标包括总路径长度、平滑度、最大速度、修正谱弧长(SPARC)和对数无量纲急动度(LDLJ)。主要临床结果是使用 Sealed Envelope Ltd. 2012 进行的手术时间(功率 90%,5%显著性)。次要临床结果是修复的水密性、CO[Formula: see text] 充气量和 OSATS 评分。结果表明,总路径长度和 LDLJ 有很大差异。与 2D 视觉相比,3D 视觉下的手术时间明显缩短([Formula: see text] 分钟与[Formula: see text] 分钟;p [Formula: see text] 0.026)。这些结果表明,在胎儿镜 SBA 修复中断缝合过程中,3D 视觉可提高手术性能。为了确认这些结果,建议进行一项涉及多个专家和新手外科医生的更大规模的后续研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92bd/10684542/5e316b5cfe53/41598_2023_47531_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92bd/10684542/d97ad8c042e8/41598_2023_47531_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92bd/10684542/c8e3c1bd7ec7/41598_2023_47531_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92bd/10684542/138c52dea4a7/41598_2023_47531_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92bd/10684542/5e316b5cfe53/41598_2023_47531_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92bd/10684542/d97ad8c042e8/41598_2023_47531_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92bd/10684542/c8e3c1bd7ec7/41598_2023_47531_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92bd/10684542/138c52dea4a7/41598_2023_47531_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92bd/10684542/5e316b5cfe53/41598_2023_47531_Fig4_HTML.jpg

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本文引用的文献

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2
Development of a simulator for training of fetoscopic myelomeningocele surgery.开发一种用于培训胎儿镜脊膜膨出手术的模拟器。
Prenat Diagn. 2023 Mar;43(3):355-358. doi: 10.1002/pd.6308. Epub 2023 Feb 2.
3
Neuroprotection is improved by watertightness of fetal spina bifida repair in the sheep model.
在绵羊模型中,胎儿脊柱裂修复的水密性可改善神经保护作用。
Ultrasound Obstet Gynecol. 2023 Jan;61(1):81-92. doi: 10.1002/uog.24907.
4
Validation of a high-fidelity training model for fetoscopic spina bifida surgery.验证用于胎儿镜脊柱裂手术的高保真培训模型。
Sci Rep. 2021 Mar 17;11(1):6109. doi: 10.1038/s41598-021-85607-6.
5
Comparison of two- and three-dimensional endoscopic visualization for fetal myelomeningocele repair: a pilot study using a fetoscopic surgical simulator.二维与三维内镜可视化在胎儿脊膜膨出修补术中的比较:使用胎儿镜手术模拟器的初步研究。
Childs Nerv Syst. 2021 May;37(5):1613-1621. doi: 10.1007/s00381-020-04999-4. Epub 2021 Jan 4.
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Learning curves of open and endoscopic fetal spina bifida closure: systematic review and meta-analysis.开放式和内镜下胎儿脊柱裂闭合术的学习曲线:系统评价和荟萃分析。
Ultrasound Obstet Gynecol. 2020 Jun;55(6):730-739. doi: 10.1002/uog.20389.
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