Department of Pediatrics, Soroka University Medical Center, Beer-Sheva, Israel.
Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Eur J Pediatr. 2024 Feb;183(2):815-825. doi: 10.1007/s00431-023-05347-9. Epub 2023 Nov 29.
Foreign body aspiration (FBA) is a common cause of pediatric morbidity, but a standardized protocol to guide decision-making about bronchoscopy is lacking. We aimed to validate a new Foreign body aspiration score (FOBAS) for the pediatric emergency department (ED). Patients aged 0-18 years referred to the ED for suspected FBA were prospectively enrolled. FOBAS was calculated according to clinical features of a choking episode, sudden cough, exposure to nuts, absence of fever and rhinitis, stridor, and unilateral auscultatory and radiological findings. FBA risk was evaluated based on the total score (low, 1-3; moderate, 4-6; high, 7-10). Low-risk children were discharged from the ED and followed clinically. Moderate-risk children were hospitalized and evaluated by a pediatric pulmonologist, and high-risk children were referred directly for therapeutic bronchoscopy. Among the 100 enrolled children (59% males; median age 20 [interquartile range 11-39] months), a foreign body was diagnosed in 1/49 (2%), 14/41 (34.1%), and 9/10 (90%) with low, moderate, and high FOBAS, respectively (P < .001). Logistic regression indicated a higher risk for FBA with higher scores. The odds ratio for each additional point was 2.75 (95% confidence interval 1.78-4.24), and FOBAS showed a high predictive value for FBA (area under the curve 0.89). FOBAS implementation significantly reduced the rate of negative bronchoscopies, from 67.4% annually during 2016-2019 to 50% in 2020 (P = .042).
FOBAS reliably predicts FBA in cases of suspected FBA and improves management and in-hospital decision-making.
• Foreign body aspiration is a major cause of pediatric morbidity and mortality. • Currently, there is no unified protocol for children referred to the emergency department for suspected FBA, therefore, a well-defined algorithm is needed to improve the decision-making process.
• The pediatric Foreign body aspiration score (FOBAS) is a new, prospectively validated clinical score that shows high sensitivity and specificity for the presence of FBA in children. • FOBAS reduces unnecessary admissions and invasive procedures and leads to better clinical outcomes.
验证一种新的儿童急诊室(ED)异物吸入评分(FOBAS)。
前瞻性纳入因疑似异物吸入而转诊至 ED 的 0-18 岁患儿。根据窒息发作、突然咳嗽、暴露于坚果、无发热和鼻炎、喘鸣、单侧听诊和影像学发现的临床特征计算 FOBAS。根据总分(低危:1-3 分;中危:4-6 分;高危:7-10 分)评估异物吸入风险。低危患儿从 ED 出院并进行临床随访。中危患儿住院并由儿科肺科医生评估,高危患儿直接行治疗性支气管镜检查。
100 例患儿中(59%为男性;中位年龄 20 个月[11-39 个月]),低、中、高危 FOBAS 患儿中分别有 1 例(2%)、14 例(34.1%)和 9 例(90%)诊断为异物,差异有统计学意义(P<0.001)。Logistic 回归分析显示,FOBAS 评分越高,异物吸入风险越高。每增加 1 分,比值比为 2.75(95%置信区间 1.78-4.24),FOBAS 对异物吸入有较高的预测价值(曲线下面积 0.89)。FOBAS 的实施显著降低了阴性支气管镜检查率,从 2016-2019 年每年的 67.4%降至 2020 年的 50%(P=0.042)。
FOBAS 能可靠预测疑似异物吸入患儿的异物吸入情况,改善管理和院内决策。