Safwat Nardine, Mahmoud Amr M, Abdel-Ghany Maha F, Ayad Miriam F
Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Ain Shams University, Abbassia, 11566, Cairo, Egypt.
Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr-El Aini Street, Cairo, 11562, Egypt.
BMC Chem. 2023 Nov 28;17(1):170. doi: 10.1186/s13065-023-01092-0.
Environmental appearance of antimicrobials due to frequent use of personal care products as recommended by WHO can cause serious flare-up of antimicrobial resistance. In this work, three eco-friendly microfabricated copper solid-state sensors were developed for measuring triclosan in water. Multi-walled carbon nanotubes were incorporated in sensor 2 and 3 as hydrophobic conductive inner layer. Meanwhile, β-cyclodextrin was incorporated in sensor 3 as an ionophore for selective binding of TCS in presence of interfering compounds. The obtained linear responses of sensors 1, 2 and 3 were (1 × 10-1 × 10 M), (1 × 10-1 × 10 M) and (1 × 10- 1 × 10 M), respectively. Limit of detection was 9.87 × 10 M, 9.62 × 10 M, and 9.94 × 10 M, respectively. The miniaturized sensors were utilized for monitoring of triclosan in water samples.
按照世界卫生组织的建议，由于频繁使用个人护理产品而导致的抗菌剂环境出现可能会引发严重的抗菌素耐药性问题。在这项工作中，开发了三种环保型微制造铜固态传感器用于测量水中的三氯生。在传感器2和3中加入多壁碳纳米管作为疏水导电内层。同时，在传感器3中加入β-环糊精作为离子载体，以便在存在干扰化合物的情况下选择性结合三氯生。传感器1、2和3获得的线性响应分别为(1×10⁻¹×10 M)、(1×10⁻¹×10 M)和(1×10⁻¹×10 M)。检测限分别为9.87×10 M、9.62×10 M和9.94×10 M。这些小型化传感器用于监测水样中的三氯生。
