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多种职业健康风险评估模型在石雕工矽尘中的应用。

Application of Multiple Occupational Health Risk Assessment Models for Crystalline Silica Dust among Stone Carvers.

机构信息

Department of Occupational Health Engineering, Neyshabur University of Medical Sciences, Neyshabur, Iran.

Student Research Committee, Neyshabur University of Medical Sciences, Iran.

出版信息

Asian Pac J Cancer Prev. 2023 Nov 1;24(11):3999-4005. doi: 10.31557/APJCP.2023.24.11.3999.

Abstract

OBJECTIVE

Silica is the most abundant substance on the Earth's crust and is a proven carcinogen. The aim of this study was to measure the occupational exposure of stone carvers to crystalline silica and to evaluate the health risks.  Methods: This descriptive and analytical cross-sectional study was performed on 79 stone carvers. Inhalation air sampling was performed by the NIOSH7500 method and the amount of silica was determined by X-ray diffraction (XRD). Semi-quantitative and quantitative risk assessments were performed using the methods of the Singapore Department and the US Environmental Protection Agency (EPA), respectively. Mortality due to silicosis and lung cancer were estimated using the Manettej and Rice models. Data were analyzed using SPSS23 software.

RESULTS

The mean exposure to total inhalable dust and crystalline silica among the stone carvers was 1.44 and 0.5 mg/m3, respectively. Exposure to total dust and silica was significantly higher than the occupational standard (P <0.0001). Stone carvers' exposure to silica was at very high-risk level, and the carcinogenicity of silica considering two cancer slopes was 7.40 × 10-6 and 3.12 × 10-7 and the risk of non-carcinogenicity was unacceptable.

CONCLUSION

The mortality rate due to silicosis was between 3 and 12 people per thousand, and due to lung cancer was 150.24 people per thousand. Based on the results of risk assessment, serious control measures should be implemented in order to reduce workers' exposure to silica.

摘要

目的

二氧化硅是地壳中最丰富的物质,已被证实为一种致癌物质。本研究旨在测量石雕工人接触结晶二氧化硅的职业暴露情况并评估健康风险。

方法

这是一项描述性和分析性的横断面研究,共纳入 79 名石雕工人。采用 NIOSH7500 法进行吸入性空气采样,并用 X 射线衍射(XRD)测定二氧化硅含量。分别采用新加坡卫生部和美国环境保护署(EPA)的方法进行半定量和定量风险评估。采用 Manettej 和 Rice 模型估计矽肺和肺癌的死亡率。数据采用 SPSS23 软件进行分析。

结果

石雕工人总可吸入粉尘和结晶二氧化硅的平均暴露量分别为 1.44mg/m3 和 0.5mg/m3。总粉尘和二氧化硅的暴露量明显高于职业标准(P<0.0001)。石雕工人的二氧化硅暴露水平处于极高风险水平,考虑到两种癌症斜率,二氧化硅的致癌性为 7.40×10-6和 3.12×10-7,非致癌风险不可接受。

结论

矽肺的死亡率在每千人 3 至 12 人之间,肺癌的死亡率为每千人 150.24 人。基于风险评估的结果,应采取严格的控制措施,以降低工人接触二氧化硅的水平。

相似文献

本文引用的文献

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A brief review of silicosis in the United States.美国矽肺病简述。
Environ Health Insights. 2010 May 18;4:21-6. doi: 10.4137/ehi.s4628.

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