Janostiakova Nikola, Gnip Andrej, Kodada Dominik, Saade Rami, Blandova Gabriela, Mikova Emilia, Tibenska Elena, Repiska Vanda, Minarik Gabriel
Institute of Medical Biology, Genetics and Clinical Genetics, Faculty of Medicine, Comenius University, Bratislava, Slovakia.
Medirex, a.s., Pezinok, Slovakia.
Front Med (Lausanne). 2023 Nov 6;10:1225596. doi: 10.3389/fmed.2023.1225596. eCollection 2023.
The COVID-19 pandemic has been part of Slovakia since March 2020. Intensive laboratory testing ended in October 2022, when the number of tests dropped significantly, but the state of the pandemic continues to this day. For the management of COVID-19, it is important to find an indicator that can predict pandemic changes in the community. The average daily/weekly Ct value with a certain time delay can predict changes in the number of cases of SARS-CoV-2 infection, which can be a useful indicator for the healthcare system. The study analyzed the results of 1,420,572 RT-qPCR tests provided by one accredited laboratory during the ongoing pandemic in Slovakia from March 2020 to September 2022. The total positivity of the analyzed tests was 24.64%. The average Ct values found were the highest in the age group of 3-5 years, equal to the number 30.75; the lowest were in the age group >65 years, equal to the number 27. The average weekly Ct values ranged from 22.33 (pandemic wave week) to 30.12 (summer week). We have summarized the results of SARS-CoV-2 diagnostic testing in Slovakia with the scope defined by the rate and positivity of tests carried out at Medirex a.s. laboratories.
自2020年3月以来,新冠疫情一直影响着斯洛伐克。密集的实验室检测于2022年10月结束,当时检测数量大幅下降,但疫情状况一直持续到今天。对于新冠疫情的管理而言,找到一个能够预测社区疫情变化的指标非常重要。具有一定时间延迟的平均每日/每周Ct值可以预测新冠病毒感染病例数的变化,这对医疗系统来说可能是一个有用的指标。该研究分析了斯洛伐克一家认可实验室在2020年3月至2022年9月期间持续的疫情期间提供的1,420,572次逆转录定量聚合酶链反应(RT-qPCR)检测结果。分析检测的总阳性率为24.64%。发现的平均Ct值在3至5岁年龄组中最高,为30.75;在65岁以上年龄组中最低,为27。平均每周Ct值范围从22.33(疫情高峰期周)到30.12(夏季周)。我们总结了斯洛伐克新冠病毒诊断检测的结果,范围由Medirex a.s.实验室进行检测的速率和阳性率界定。