Be mindful of potential pitfalls when using the Cre-LoxP system in cancer research.
作者信息
Czarnota Piotr, Cisowski Jaroslaw
出版信息
Oncoscience. 2023 Nov 14;10:67-68. doi: 10.18632/oncoscience.591. eCollection 2023.
Abstract
摘要
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Be mindful of potential pitfalls when using the Cre-LoxP system in cancer research.在癌症研究中使用Cre-LoxP系统时，要留意潜在的陷阱。
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本文引用的文献
1
Current view of liver cancer cell-of-origin and proposed mechanisms precluding its proper determination.当前对肝癌细胞起源的看法以及阻碍其准确判定的推测机制。
Cancer Cell Int. 2023 Jan 6;23(1):3. doi: 10.1186/s12935-022-02843-0.
2
The role of DNA demethylation in liver to pancreas transdifferentiation.DNA 去甲基化在肝向胰腺转分化中的作用。
Stem Cell Res Ther. 2022 Sep 16;13(1):476. doi: 10.1186/s13287-022-03159-6.
3
Alagille syndrome: clinical perspectives.阿拉吉耶综合征：临床视角
Appl Clin Genet. 2016 Jun 30;9:75-82. doi: 10.2147/TACG.S86420. eCollection 2016.
4
Studying extracellular vesicle transfer by a Cre-loxP method.通过 Cre-loxP 方法研究细胞外囊泡的转移。
Nat Protoc. 2016 Jan;11(1):87-101. doi: 10.1038/nprot.2015.138. Epub 2015 Dec 10.
5
p53-dependent Nestin regulation links tumor suppression to cellular plasticity in liver cancer.p53 依赖性巢蛋白调控将肝癌中的肿瘤抑制与细胞可塑性联系起来。
Cell. 2014 Jul 31;158(3):579-92. doi: 10.1016/j.cell.2014.05.051.
6
Hippo pathway activity influences liver cell fate.河马通路活性影响肝细胞命运。
Cell. 2014 Jun 5;157(6):1324-1338. doi: 10.1016/j.cell.2014.03.060.
7
Alveolar progenitor and stem cells in lung development, renewal and cancer.肺发育、更新和癌症中的肺泡祖细胞和干细胞。
Nature. 2014 Mar 13;507(7491):190-4. doi: 10.1038/nature12930. Epub 2014 Feb 5.
8
Pancreas-specific Cre driver lines and considerations for their prudent use.胰腺特异性 Cre 驱动系及其谨慎使用的注意事项。
Cell Metab. 2013 Jul 2;18(1):9-20. doi: 10.1016/j.cmet.2013.06.011.
9
Robust cellular reprogramming occurs spontaneously during liver regeneration.肝脏再生过程中会自发地进行稳健的细胞重编程。
Genes Dev. 2013 Apr 1;27(7):719-24. doi: 10.1101/gad.207803.112. Epub 2013 Mar 21.
10
The Cre-loxP system: a versatile tool for targeting genes in a cell- and stage-specific manner.Cre-loxP系统：一种以细胞和阶段特异性方式靶向基因的通用工具。
Cell Transplant. 2000 Nov-Dec;9(6):805-15. doi: 10.1177/096368970000900607.
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