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二尖瓣狭窄患者接受原位肝移植的麻醉考量

Anesthetic Considerations for Patients With Mitral Stenosis Undergoing Orthotopic Liver Transplant.

作者信息

Mitchell Justin, Alnemer Amar, Deiparine Selina, Stein Erica, Gorelik Leonid

机构信息

Anesthesiology, University of California, Los Angeles (UCLA) Medical Center, Los Angeles, USA.

Anesthesiology, The Ohio State University College of Medicine, Columbus, USA.

出版信息

Cureus. 2023 Oct 26;15(10):e47751. doi: 10.7759/cureus.47751. eCollection 2023 Oct.

Abstract

A 70-year-old male presented for an orthotopic liver transplant (OLT) with co-existing moderate-severe mitral valve stenosis. The hemodynamic goals of managing mitral stenosis posed a significant additional challenge to this patient's care. Intraoperative transesophageal echocardiography (TEE) was critical in guiding volume status and resuscitation. In addition, the patient's valvulopathy guided our vasoactive medication selection and arrhythmia prevention. In this article, we describe the multidisciplinary discussions regarding preoperative valvular intervention as well as the intraoperative techniques used to preserve cardiac output while avoiding coagulopathy and arrhythmias. We discuss the pathophysiology of valvular disease in the context of liver failure and the guidelines by which this disease process is classified. In addition, we discuss the benefits and limitations of intraoperative TEE in evaluating this unique physiology.

摘要

一名70岁男性因原位肝移植(OLT)就诊,同时患有中度至重度二尖瓣狭窄。二尖瓣狭窄管理的血流动力学目标给该患者的护理带来了重大的额外挑战。术中经食管超声心动图(TEE)在指导容量状态和复苏方面至关重要。此外,患者的瓣膜病指导了我们血管活性药物的选择和心律失常的预防。在本文中,我们描述了关于术前瓣膜干预的多学科讨论以及用于维持心输出量同时避免凝血障碍和心律失常的术中技术。我们在肝衰竭背景下讨论瓣膜病的病理生理学以及该疾病过程的分类指南。此外,我们讨论了术中TEE在评估这种独特生理学方面的益处和局限性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6632/10676281/3fbd586d1a63/cureus-0015-00000047751-i01.jpg

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