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仅行肿块切除术的年轻男性睾丸浆液性交界性卵巢上皮样肿瘤:一例报告

Serous Borderline Ovarian Epithelial Type Tumors of Testis in A Young Man with Only Mass Resection: A Case Report.

作者信息

Rahimi Mandana, Moradi Yasaman, Khaleghimehr Farhood

机构信息

Department of Pathology, Hasheminejad Kidney Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Department of Urology, Hasheminejad Kidney Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

出版信息

Iran J Pathol. 2023;18(4):476-479. doi: 10.30699/IJP.2023.547886.2880. Epub 2023 Oct 15.

DOI:10.30699/IJP.2023.547886.2880
PMID:38024554
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10646748/
Abstract

Tumors of the ovarian epithelial type of testis are an infrequent entity. We report a case of borderline serous tumor in an 18-year-old male who presented with a right testicular mass, clinically suspicious of carcinoma. After right inguinal exploration, two pedunculated para-testicular masses were identified in the appendix of the right testis and epididymis. The histological features were as complex papillary structures lined by columnar cells with mild to moderate pleomorphism. Microscopically, features of borderline serous testicular tumors are identical to the morphology of the same tumors encountered in the ovarian counterparts. These tumors usually reveal papillae with fibrovascular cores lined by stratified cuboidal to columnar epithelium. This case highlights a need for clinicians and pathologists to be aware of this infrequent entity and improve the best patient management attitude. Serous epithelial tumors are common ovary tumors but are very rare entities in the testis. These tumors originate from the remnant of Mullerian ducts or Mullerian metaplasia of tunica vaginalis and are nonaggressive, even associated with extra ovarian spread, and have outstanding prognosis. A review of the literature has shown nearly fifty reported cases worldwide, and most of the cases occur in young to middle-aged adults.

摘要

睾丸卵巢上皮型肿瘤是一种罕见的疾病。我们报告一例18岁男性的交界性浆液性肿瘤,该患者表现为右侧睾丸肿块,临床上怀疑为癌。经右腹股沟探查,在右侧睾丸附件和附睾中发现两个带蒂的睾丸旁肿块。组织学特征为柱状细胞衬覆的复杂乳头结构,具有轻度至中度异型性。显微镜下,睾丸交界性浆液性肿瘤的特征与卵巢同类肿瘤的形态相同。这些肿瘤通常表现为具有纤维血管轴心的乳头,内衬复层立方上皮至柱状上皮。该病例强调临床医生和病理学家需要了解这种罕见疾病,并改善最佳的患者管理态度。浆液性上皮肿瘤是常见的卵巢肿瘤,但在睾丸中是非常罕见的疾病。这些肿瘤起源于苗勒管残余或鞘膜的苗勒化生,无侵袭性,即使伴有卵巢外扩散,预后也良好。文献综述显示,全球报告的病例近50例,大多数病例发生在中青年。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a011/10646748/ca1c2e03b2bd/ijp-18-476-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a011/10646748/59fda49fa6e1/ijp-18-476-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a011/10646748/ca1c2e03b2bd/ijp-18-476-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a011/10646748/59fda49fa6e1/ijp-18-476-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a011/10646748/ca1c2e03b2bd/ijp-18-476-g002.jpg

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本文引用的文献

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Serous borderline tumor with micropapillary pattern of the right ovary that developed 6 recurrences over 30 years after primary surgery.右侧卵巢浆液性交界性肿瘤伴微乳头结构,在初次手术后30年内复发6次。
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Selected other problematic testicular and paratesticular lesions: rete testis neoplasms and pseudotumors, mesothelial lesions and secondary tumors.
其他选定的有问题的睾丸和睾丸旁病变:睾丸网肿瘤和假瘤、间皮病变及继发性肿瘤。
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Serous borderline tumor of the paratestis: a report of seven cases.睾丸旁浆液性交界性肿瘤:7例报告
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Testicular and paratesticular tumors and tumor-like lesions of ovarian common epithelial and müllerian types. A report of four cases and review of the literature.睾丸及睾丸旁肿瘤以及卵巢常见上皮和苗勒氏类型的肿瘤样病变。4例报告并文献复习。
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