Janbu T, Løkken P, Nesheim B I
Acta Obstet Gynecol Scand Suppl. 1979;87:81-5. doi: 10.3109/00016347909157796.
The analgesic effect of paracetamol, acetyl-salicylic acid, and placebo on dysmenorrhea were compared in a double-blind cross-over study of 30 women. There was a moderate placebo effect, but no significant difference was found between the three treatments. Blood loss was also measured and it did not vary, with the type of drug ingested. It is concluded that paracetamol and acetylsalicylic acid in the doses used (0.5 g x 4 for 3 days) were not effective against heavy dysmenorrhea, and that none of the drugs influenced the amount of blood lost.
在一项针对30名女性的双盲交叉研究中,比较了对乙酰氨基酚、乙酰水杨酸和安慰剂对痛经的镇痛效果。存在中度安慰剂效应,但三种治疗方法之间未发现显著差异。还测量了失血量,其并未因所摄入药物的类型而有所不同。得出的结论是,所用剂量的对乙酰氨基酚和乙酰水杨酸(0.5克×4,服用3天)对重度痛经无效,且没有一种药物影响失血量。