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乙酰水杨酸、对乙酰氨基酚和安慰剂对痛经女性疼痛及失血的影响。

Effect of acetylsalicylic acid, paracetamol and placebo on pain and blood loss in dysmenorrheic women.

作者信息

Janbu T, Løkken P, Nesheim B I

出版信息

Acta Obstet Gynecol Scand Suppl. 1979;87:81-5. doi: 10.3109/00016347909157796.

DOI:10.3109/00016347909157796
PMID:380253
Abstract

The analgesic effect of paracetamol, acetyl-salicylic acid, and placebo on dysmenorrhea were compared in a double-blind cross-over study of 30 women. There was a moderate placebo effect, but no significant difference was found between the three treatments. Blood loss was also measured and it did not vary, with the type of drug ingested. It is concluded that paracetamol and acetylsalicylic acid in the doses used (0.5 g x 4 for 3 days) were not effective against heavy dysmenorrhea, and that none of the drugs influenced the amount of blood lost.

摘要

在一项针对30名女性的双盲交叉研究中,比较了对乙酰氨基酚、乙酰水杨酸和安慰剂对痛经的镇痛效果。存在中度安慰剂效应,但三种治疗方法之间未发现显著差异。还测量了失血量,其并未因所摄入药物的类型而有所不同。得出的结论是,所用剂量的对乙酰氨基酚和乙酰水杨酸(0.5克×4,服用3天)对重度痛经无效,且没有一种药物影响失血量。

相似文献

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Effect of acetylsalicylic acid, paracetamol and placebo on pain and blood loss in dysmenorrheic women.乙酰水杨酸、对乙酰氨基酚和安慰剂对痛经女性疼痛及失血的影响。
Acta Obstet Gynecol Scand Suppl. 1979;87:81-5. doi: 10.3109/00016347909157796.
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Effect of acetylsalicylic acid, paracetamol, and placebo on pain and blood loss in dysmenorrhoeic women.
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引用本文的文献

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Nonsteroidal anti-inflammatory drugs for dysmenorrhoea.用于痛经的非甾体抗炎药。
Cochrane Database Syst Rev. 2015 Jul 30;2015(7):CD001751. doi: 10.1002/14651858.CD001751.pub3.
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Dysmenorrhoea and prostaglandins: pharmacological and therapeutic considerations.痛经与前列腺素:药理学及治疗学考量
Drugs. 1981 Jul;22(1):42-56. doi: 10.2165/00003495-198122010-00003.