罕见的丙戊酸钠诱导的高氨血症性脑病病例。
Unusual case of sodium valproate-induced hyperammonaemia encephalopathy.
机构信息
Psychiatry, Gold Coast University Hospital, Southport, Queensland, Australia.
Psychiatry, Gold Coast University Hospital, Southport, Queensland, Australia
出版信息
BMJ Case Rep. 2023 Nov 30;16(11):e256796. doi: 10.1136/bcr-2023-256796.
Abstract
There is limited information about sodium valproate-induced hyperammonaemia encephalopathy (VPAIHE). The aim of this case report is to provide medical practitioners with a greater awareness of the possible development of hyperammonaemia due to sodium valproate use and its associated complications.This paper describes a middle-aged man with a history of bipolar affective disorder who was admitted with a manic relapse secondary to medication non-compliance. His admission was complicated by an intensive care unit admission to manage medical compromise in the context of sodium VPAIHE.
摘要
关于丙戊酸钠引起的高氨血症性脑病（VPAIHE）的信息有限。本病例报告的目的是提高医务人员对丙戊酸钠使用引起的高氨血症及其相关并发症可能发展的认识。本文描述了一名中年男子，有双相情感障碍病史，因药物不依从而导致躁狂复发入院。他入院后因钠 VPAIHE 并发的医疗并发症而住进重症监护病房。
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Clin Pharmacokinet. 2022 Oct;61(10):1345-1363. doi: 10.1007/s40262-022-01171-w. Epub 2022 Aug 30.
2
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J Med Case Rep. 2020 Jan 25;14(1):19. doi: 10.1186/s13256-020-2343-x.
3
Risk factors for valproic acid induced hyperammonemia and its association with cognitive functions.导致丙戊酸引起的高血氨的风险因素及其与认知功能的关系。
Gen Hosp Psychiatry. 2019 Jul-Aug;59:67-72. doi: 10.1016/j.genhosppsych.2019.05.005. Epub 2019 May 31.
4
Valproate-induced hyperammonemia - uncovering an underlying inherited metabolic disorder: a case report.丙戊酸盐诱发的高氨血症——揭示一种潜在的遗传性代谢紊乱：病例报告
J Med Case Rep. 2018 May 17;12(1):134. doi: 10.1186/s13256-018-1666-3.
5
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Ind Psychiatry J. 2017 Jan-Jun;26(1):99-102. doi: 10.4103/ipj.ipj_37_16.
6
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Cureus. 2017 Aug 22;9(8):e1593. doi: 10.7759/cureus.1593.
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