Fahey Kieren P, Gelbart Ben, Oberender Felix, Thompson Jenny, Rozen Tom, James Christopher, McLaren Catriona, Sniderman Jonathan, Uahwatanasakul Wonie
Paediatric Intensive Care Unit, Royal Children's Hospital Melbourne, Melbourne, VIC, Australia.
Department of Paediatrics, University of Melbourne, Melbourne, VIC, Australia.
Crit Care Resusc. 2023 Oct 18;23(3):292-299. doi: 10.51893/2021.3.OA6. eCollection 2021 Sep 6.
To investigate the rate of interhospital emergency transport for bronchiolitis and intensive care admission following the introduction of high flow nasal cannula and standardised paediatric observation and response charts. Retrospective cohort study. A statewide paediatric intensive care transport service and its two referral paediatric intensive care units (PICUs) in Victoria, Australia. Children less than 2 years old emergently transported with bronchiolitis during two time periods: 2008-2012 and 2015-2019. Incidence rates of bronchiolitis transport episodes, PICU admissions and respiratory support. 802 children with bronchiolitis were transported during the study period, 233 in the first period (2008-2012) and 569 in the second period (2015-2019). The rate of interhospital transport for bronchiolitis increased from 32.9 to 71.8 per 100 000 children aged 0-2 years. The population-adjusted rate of PICU admission increased from 16.2 to 36.6 per 100 000 children aged 0-2 years. Metropolitan hospitals were the predominant referral source and this increased from 60.1% of transports to 78.6% ( < 0.001). In children admitted to a PICU, the administration of high flow nasal cannula during transport increased significantly from 1.7% to 75.9% ( < 0.001) and a concomitant reduction in continuous positive airway pressure and mechanical ventilation occurred (40-12.4% and 27-6.9% respectively; < 0.001). The proportion of mechanical ventilation as well as PICU and hospital length of stay decreased over time. The population-adjusted rate of interhospital transport and admission to the PICU for bronchiolitis increased over time. This occurred despite a lower rate of non-invasive and invasive mechanical ventilation during transport and in the PICU.
为调查在引入高流量鼻导管以及标准化儿科观察与反应图表后,细支气管炎的院际紧急转运率和重症监护病房收治率。回顾性队列研究。澳大利亚维多利亚州的一项全州范围的儿科重症监护转运服务及其两家转诊儿科重症监护病房(PICUs)。在两个时间段内紧急转运的2岁以下细支气管炎患儿:2008 - 2012年和2015 - 2019年。细支气管炎转运事件、PICU收治情况及呼吸支持的发生率。在研究期间,802名患有细支气管炎的儿童被转运,第一阶段(2008 - 2012年)有233名,第二阶段(2015 - 2019年)有569名。0 - 2岁儿童中,细支气管炎的院际转运率从每10万名儿童32.9例增至71.8例。0 - 2岁儿童中,经人口调整后的PICU收治率从每10万名儿童16.2例增至36.6例。大都市医院是主要的转诊来源,这一比例从转运病例的60.1%增至78.6%(<0.001)。在入住PICU的儿童中,转运期间高流量鼻导管应用率从1.7%显著增至75.9%(<0.001),同时持续气道正压通气和机械通气的应用率出现下降(分别从40%降至12.4%以及从27%降至6.9%;<0.001)。机械通气比例以及PICU住院时间和总住院时间随时间减少。细支气管炎的院际转运率和入住PICU的经人口调整后的收治率随时间增加。尽管在转运期间和PICU中非侵入性和侵入性机械通气率较低,但仍出现了这种情况。