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毛细支气管炎中使用高流量湿化鼻导管吸氧可减少有创通气需求,但不能减少重症监护病房收治率。

Humidified high-flow nasal cannula oxygen in bronchiolitis reduces need for invasive ventilation but not intensive care admission.

作者信息

Goh Chong Tien, Kirby Lynette J, Schell David N, Egan Jonathan R

机构信息

Paediatric Intensive Care Unit, The Children's Hospital at Westmead, Sydney, New South Wales, Australia.

出版信息

J Paediatr Child Health. 2017 Sep;53(9):897-902. doi: 10.1111/jpc.13564. Epub 2017 May 23.

DOI:10.1111/jpc.13564
PMID:28544665
Abstract

AIM

To describe the changes to paediatric intensive care unit (PICU) admission patterns and ventilation requirements for children with bronchiolitis following the introduction of humidified high-flow nasal cannula oxygen outside the PICU.

METHODS

Retrospective study comparing patients <24 months of age with a discharge diagnosis of bronchiolitis admitted to the PICU. A comparison was made between those before humidified high-flow nasal cannula oxygen use (year 2008) to those immediately following the introduction of humidified high-flow nasal cannula oxygen use (year 2011) and those following further consolidation of humidified high-flow nasal cannula oxygen use outside the PICU (year 2013).

RESULTS

Humidified high-flow nasal cannula oxygen use up to 1 L/kg/min in the hospital did not reduce PICU admission. Intubation rates were reduced from 22.2% in 2008 to 7.8% in 2013. There was a non-significant trend towards decreased length of stay in the PICU while hospital length of stay showed a significant decrease following the introduction of humidified high-flow nasal cannula oxygen. Age <6 months and respiratory syncytial virus bronchiolitis were associated with an increased chance of failing humidified high-flow nasal cannula oxygen therapy.

CONCLUSION

Humidified high-flow nasal cannula oxygen utilised outside of the PICU in our institution for children with bronchiolitis did not reduce admission rates or length of stay to the PICU but was associated with a decreasing need for invasive ventilation and reduced hospital length of stay.

摘要

目的

描述在儿科重症监护病房(PICU)外引入高流量加温湿化鼻导管吸氧后,毛细支气管炎患儿的PICU入院模式和通气需求的变化。

方法

对入住PICU且出院诊断为毛细支气管炎的<24个月龄患儿进行回顾性研究。比较高流量加温湿化鼻导管吸氧使用前(2008年)、使用后即刻(2011年)以及PICU外高流量加温湿化鼻导管吸氧进一步巩固使用后(2013年)的患儿情况。

结果

在医院内使用流量高达1L/kg/min的高流量加温湿化鼻导管吸氧并未降低PICU入院率。插管率从2008年的22.2%降至2013年的7.8%。PICU住院时间有缩短趋势但无统计学意义,而引入高流量加温湿化鼻导管吸氧后住院总时长显著缩短。年龄<6个月以及呼吸道合胞病毒毛细支气管炎与高流量加温湿化鼻导管吸氧治疗失败几率增加相关。

结论

在我院,PICU外对毛细支气管炎患儿使用高流量加温湿化鼻导管吸氧并未降低PICU入院率或住院时间,但与有创通气需求减少及住院总时长缩短相关。

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