Shekhawat Anil Singh, Mathur Rahul, Sarkar Siddharth, Kaloiya Gauri Shanker, Balhara Yatan Pal Singh
Department of Psychiatry and NDDTC, All India Institute of Medical Sciences, New Delhi, Delhi, India.
J Neurosci Rural Pract. 2023 Oct-Dec;14(4):710-716. doi: 10.25259/JNRP_79_2023. Epub 2023 Jun 24.
Effective interventions for cannabis use disorders are fairly limited. The present randomized controlled trial (RCT) aimed to compare the reduction in cannabis use (number of days cannabis used) with brief intervention and simple advice in patients with cannabis use disorder.
This non-blinded and parallel two-group RCT included 100 male patients with cannabis use disorder. A semi-structured pro forma and severity of dependence scale (SDS) were used. Participants were then randomized to either of the two arms (brief intervention and simple advice) in a 1:1 ratio. Cannabis use patterns and SDS scores were assessed over the phone at week 4, week 8, and week 12.
The two groups were comparable in sociodemographics and cannabis use characteristics. Participants in both groups were using cannabis for 30 days in the past month before enrolment. The brief intervention group had a lesser number of days of cannabis use vis-a-vis the simple advice group at 4, 8, and 12 weeks. There was a significant time effect for change in SDS scores (F = 30.629, < 0.001), but the group effect was not significant (F = 0.379, = 0.541).
In this population of regular cannabis users, brief intervention may be useful in reducing cannabis usage. It can be integrated into routine assessments and management of those with regular use of cannabis.
针对大麻使用障碍的有效干预措施相当有限。本随机对照试验（RCT）旨在比较大麻使用障碍患者通过简短干预和简单建议在减少大麻使用量（使用大麻的天数）方面的效果。
这项非盲法平行两组RCT纳入了100名患有大麻使用障碍的男性患者。使用了半结构化表格和依赖性严重程度量表（SDS）。然后将参与者以1:1的比例随机分为两组（简短干预组和简单建议组）。在第4周、第8周和第12周通过电话评估大麻使用模式和SDS评分。
两组在社会人口统计学和大麻使用特征方面具有可比性。两组参与者在入组前的过去一个月中都有30天使用大麻。在第4周、第8周和第12周，简短干预组的大麻使用天数比简单建议组少。SDS评分变化存在显著的时间效应（F = 30.629，P < 0.001），但组间效应不显著（F = 0.379，P = 0.541）。
在这群经常使用大麻的人群中，简短干预可能有助于减少大麻使用。它可以纳入对经常使用大麻者的常规评估和管理中。
