应用超声向量血流成像技术评估颈动脉分叉处壁面切应力和流动湍流的特征及相关性。

Characteristics and Correlations of Wall Shear Stress and Flow Turbulence in the Carotid Bifurcation Evaluated Using an Ultrasound Vector Flow Imaging.

作者信息

Liu Mengmeng, Song Di, Hong Shaofu, Dong Yinghui, Gao Wenjing, Du Yigang, Zhu Lei, Xu Jinfeng, Dong Fajin

机构信息

Department of Ultrasound, First Affiliated Hospital of Southern University of Science and Technology, Second Clinical College of Jinan University, Shenzhen People's Hospital, Shenzhen, China,

Department of Ultrasound, First Affiliated Hospital of Southern University of Science and Technology, Second Clinical College of Jinan University, Shenzhen People's Hospital, Shenzhen, China.

出版信息

J Vasc Res. 2024;61(1):38-49. doi: 10.1159/000534738. Epub 2023 Dec 7.

DOI:10.1159/000534738

PMID:38061338

Abstract

INTRODUCTION

The aim of the study was to evaluate characteristics and provide the normal values of wall shear stress (WSS) and flow turbulence (Tur), and the relationship between them in the carotid bifurcation based on an ultrasound vector flow imaging (V Flow) in healthy adults.

METHODS

Max and mean WSS and Tur values at three segments (initial segments of internal and external carotid arteries [IICA and IECA]; distal segment of common carotid artery [DCCA]), both in anterior and posterior walls, were successfully obtained in 56 healthy adults, using ultrasound V Flow function. Relationship between mean WSS and Tur was further explored.

RESULTS

The mean WSS value was 0.71 Pa, 0.86 Pa, and 0.96 Pa at IICA, IECA, and DCCA, respectively (IICA < IECA < DCCA, p < 0.05). The mean Tur value was 13.85%, 5.46%, and 4.17% at IICA, IECA, and DCCA, respectively (IICA > IECA > DCCA, p < 0.05). A cutoff value (WSS = 0.4 Pa) was selected and Tur values were significantly higher in group with WSS cutoff value <0.4 Pa than group with WSS cutoff value ≥0.4 Pa (p < 0.01).

CONCLUSION

WSS and Tur are moderately negatively correlated, which can be used in the quantitative evaluation of carotid bifurcation and could be a potential dual-parameter tool in the clinical research for early detection of carotid atherosclerosis.

摘要

简介

本研究旨在评估健康成年人颈总动脉分叉处基于超声向量血流成像（VFlow）的壁面切应力（WSS）和流场紊乱（Tur）的特征及其正常值，并探讨二者之间的关系。

方法

使用超声 VFlow 功能，成功获得 56 例健康成年人颈总动脉三个节段（颈内、外动脉起始段[IICA 和 IECA]；颈总动脉远段[DCCA]）前、后壁最大和平均 WSS 和 Tur 值。进一步探讨平均 WSS 和 Tur 值之间的关系。

结果

IICA、IECA 和 DCCA 处的平均 WSS 值分别为 0.71 Pa、0.86 Pa 和 0.96 Pa（IICA < IECA < DCCA，p < 0.05）。IICA、IECA 和 DCCA 处的平均 Tur 值分别为 13.85%、5.46%和 4.17%（IICA > IECA > DCCA，p < 0.05）。选择一个截断值（WSS = 0.4 Pa），WSS 截断值 <0.4 Pa 组的 Tur 值明显高于 WSS 截断值≥0.4 Pa 组（p < 0.01）。