Department of Clinical Studies and Nutritional Epidemiology, Nutrition Biomed Research Institute, South Melbourne, VIC, Australia.
Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, VIC, Australia.
Eur J Clin Nutr. 2024 Apr;78(4):356-359. doi: 10.1038/s41430-023-01377-6. Epub 2023 Dec 9.
While there are emerging reports in the scientific literature on potential associations between cholesterol/lipids and prostate cancer, information on the dietary management of these cancer patients is currently lacking. We report on a 57-year-old white Australian male diagnosed with advanced prostate cancer who had personalized dietary management in preparation for and following his medical treatment: radiation and radical prostatectomy. Dietary recommendations were based on his blood results and nutrigenomic tests which showed a history of and genetic predisposition to dyslipidemia. Nutritional analysis also confirmed the need for dietary modification of his fat intake. Eighteen months post medical and dietary intervention his PSA level was reported at 0.1 ug/L and all blood lipid levels were within reference ranges. At two years there was no detectable disease recurrence and androgen deprivation therapy (ADT) was not required. Personalized dietary recommendations could be a clinically beneficial addition to the multidisciplinary management of prostate cancer patients.
虽然科学文献中有一些关于胆固醇/脂质与前列腺癌之间潜在关联的新兴报告，但目前缺乏针对这些癌症患者的饮食管理信息。我们报告了一位 57 岁的白人澳大利亚男性，他被诊断出患有晚期前列腺癌，在接受医疗治疗（放疗和根治性前列腺切除术）前后进行了个性化的饮食管理。饮食建议基于他的血液结果和营养基因组测试，这些测试显示他有血脂异常的病史和遗传易感性。营养分析还证实了需要改变他的脂肪摄入量。在接受医学和饮食干预后的 18 个月，他的 PSA 水平报告为 0.1μg/L，所有血脂水平均在参考范围内。两年后，没有发现疾病复发，也不需要雄激素剥夺治疗（ADT）。个性化的饮食建议可能是前列腺癌患者多学科管理的一种临床有益补充。
