Krammer E B, Streinzer W, Millesi W, Ellböck E, Zrunek M
Laryngol Rhinol Otol (Stuttg). 1986 Nov;65(11):617-20.
The central organisation of the internal branch of the superior laryngeal nerve was examined in the rat using the technique of intraaxonal transport of horseradish peroxidase (HRP). Application of HRP to the internal branch resulted in anterograde labelling of afferent nerve fibres as well as in retrograde labelling of perikarya within both motor nuclei of the vagus, i.e. the nucleus ambiguus and the dorsal motor nucleus. The location of retrogradely labelled neurons is confined to an area of 700 microns length near the rostral extremities of both nuclei. The internal laryngeal branch, therefore, is not entirely sensory, but contains general and special visceral efferent fibres arising in the dorsal motor nucleus and in the nucleus ambiguus, respectively. Dorsal motor neurons of the internal branch represent preganglionic parasympathetic neurons projecting to the mucous glands of the larynx, whereas efferents from the nucleus ambiguus supply striated muscle fibres of the larynx. The arytenoid and aryepiglotticus are discussed as potential targets of the internal branch of the superior laryngeal nerve.
利用辣根过氧化物酶（HRP）轴突内运输技术，对大鼠喉上神经内支的中枢组织进行了研究。将HRP应用于内支，可导致传入神经纤维的顺行标记以及迷走神经两个运动核（即疑核和迷走神经背核）内神经元胞体的逆行标记。逆行标记神经元的位置局限于两个核头端附近700微米长的区域。因此，喉内支并非完全是感觉性的，而是分别包含起源于迷走神经背核和疑核的一般内脏传出纤维和特殊内脏传出纤维。内支的迷走神经背核神经元代表投射至喉黏液腺的节前副交感神经元，而疑核的传出纤维则支配喉的横纹肌纤维。文中讨论了杓状肌和杓会厌肌作为喉上神经内支潜在靶点的情况。
