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离婚与自杀未遂风险:一项瑞典全国性研究。

Divorce and risk of suicide attempt: a Swedish national study.

机构信息

Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.

Center for Primary Health Care Research, Lund University, Malmö, Sweden.

出版信息

Psychol Med. 2024 Jun;54(8):1620-1628. doi: 10.1017/S0033291723003513. Epub 2023 Dec 12.

Abstract

BACKGROUND

Prior research has reported an association between divorce and suicide attempt. We aimed to clarify this complex relationship, considering sex differences, temporal factors, and underlying etiologic pathways.

METHODS

We used Swedish longitudinal national registry data for a cohort born 1960-1990 that was registered as married between 1978 and 2018 ( = 1 601 075). We used Cox proportional hazards models to estimate the association between divorce and suicide attempt. To assess whether observed associations were attributable to familial confounders or potentially causal in nature, we conducted co-relative analyses.

RESULTS

In the overall sample and in sex-stratified analyses, divorce was associated with increased risk of suicide attempt (adjusted hazard ratios [HRs] 1.66-1.77). Risk was highest in the year immediately following divorce (HRs 2.20-2.91) and declined thereafter, but remained elevated 5 or more years later (HRs 1.41-1.51). Divorcees from shorter marriages were at higher risk for suicide attempt than those from longer marriages (HRs 3.33-3.40 and 1.20-1.36, respectively). In general, HRs were higher for divorced females than for divorced males. Co-relative analyses suggested that familial confounders and a causal pathway contribute to the observed associations.

CONCLUSIONS

The association between divorce and risk of suicide attempt is complex, varying as a function of sex and time-related variables. Given evidence that the observed association is due in part to a causal pathway from divorce to suicide attempt, intervention or prevention efforts, such as behavioral therapy, could be most effective early in the divorce process, and in particular among females and those whose marriages were of short duration.

摘要

背景

先前的研究报告了离婚与自杀企图之间的关联。我们旨在阐明这种复杂的关系,考虑到性别差异、时间因素和潜在的病因途径。

方法

我们使用瑞典纵向全国登记数据,对 1960-1990 年出生的队列进行了研究,这些人在 1978 年至 2018 年期间登记为已婚(=1601075 人)。我们使用 Cox 比例风险模型来估计离婚与自杀企图之间的关联。为了评估观察到的关联是否归因于家族性混杂因素或具有潜在的因果关系,我们进行了亲属分析。

结果

在总体样本和性别分层分析中,离婚与自杀企图的风险增加相关(调整后的风险比[HR]为 1.66-1.77)。风险在离婚后的第一年最高(HR 为 2.20-2.91),此后逐渐下降,但 5 年或更长时间后仍处于较高水平(HR 为 1.41-1.51)。较短婚姻的离婚者比较长婚姻的离婚者自杀企图的风险更高(HR 分别为 3.33-3.40 和 1.20-1.36)。一般来说,女性离婚者的 HR 高于男性离婚者。亲属分析表明,家族性混杂因素和因果途径促成了观察到的关联。

结论

离婚与自杀企图风险之间的关联是复杂的,因性别和与时间相关的变量而异。鉴于观察到的关联部分归因于离婚到自杀企图的因果途径,因此干预或预防措施,如行为疗法,可能在离婚过程的早期最为有效,特别是在女性和婚姻持续时间较短的人群中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd39/11551852/298c0db606b0/nihms-2031893-f0001.jpg

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