Fisk N M, Anderson J C
Obstet Gynecol. 1987 Mar;69(3 Pt 2):501-3.
Serious maternal morbidity has been a feature of the few documented cases of acute intrauterine infection after chorionic villus sampling. A case is described in which infection manifested 14 days after transcervical chorion biopsy. Broad-spectrum antibiotics were begun, and ultrasound demonstrated a live fetus. After vacuum curettage was performed, repeat scan showed an empty uterus. Anaerobes isolated from the cervix both before chorionic villus sampling and during the infection were also implicated in published reports of patients developing life-threatening complications, but were not treated specifically until after morbid sequelae had occurred. Serious morbidity was avoided in this patient by aggressive management with early anaerobic cover, uterine evacuation despite the presence of a live fetus, and confirmation of complete evacuation by ultrasound.
严重的孕产妇发病是绒毛取样后少数记录在案的急性宫内感染病例的一个特征。本文描述了一例经宫颈绒毛活检14天后出现感染的病例。开始使用广谱抗生素，超声显示胎儿存活。在进行刮宫术后，重复扫描显示子宫为空。在绒毛取样前和感染期间从宫颈分离出的厌氧菌也与已发表的发生危及生命并发症的患者报告有关，但直到出现病态后遗症后才进行特异性治疗。通过积极的管理，包括早期给予厌氧菌覆盖、尽管胎儿存活仍进行子宫排空以及通过超声确认完全排空，该患者避免了严重发病。
