Baris Mine Esen, Degirmenci Cumali, Yilmaz Suzan Guven, Afrashi Filiz, Pullukcu Husnu, Tasbakan Meltem
Department of Ophthalmology, Ege University Faculty of Medicine, Izmir, Türkiye.
Department of Infectious Diseases, Ege University Faculty of Medicine, İzmir, Türkiye.
Beyoglu Eye J. 2023 Dec 1;8(4):273-279. doi: 10.14744/bej.2023.13549. eCollection 2023.
Thromboembolic complications related to the COVID-19 infection are frequently reported. This study aims to evaluate the impact of a prior non-severe COVID-19 infection on retinal microcirculation with optical coherence tomography angiography (OCTA).
A total of 83 eyes of 43 patients with a history of non-severe COVID-19 infection confirmed with a positive PCR test (Group 1) and 30 healthy controls (Group 2) underwent detailed eye examination, including optic coherence tomography angiography (OCTA, RTVue-XR Avanti) scanning. Vessel densities (VD) in the superficial capillary plexus (SCP), deep capillary plexus (DCP), and foveal avascular zone were evaluated.
The mean duration between the COVID-19 positive PCR test and ocular examination was 144.6±82.2 days. VD of SCP and DCP in the foveal and perifoveal regions were significantly lower in Group 1 compared to Group 2 (p<0.05).
A non-severe COVID-19 infection may cause a decrease in the VD of retinal SCP and DCP.
与新型冠状病毒肺炎(COVID-19)感染相关的血栓栓塞并发症屡有报道。本研究旨在通过光学相干断层扫描血管造影(OCTA)评估既往非重症COVID-19感染对视网膜微循环的影响。
对43例经聚合酶链反应(PCR)检测确诊为非重症COVID-19感染病史患者的83只眼(第1组)和30名健康对照者(第2组)进行详细的眼部检查,包括光学相干断层扫描血管造影(OCTA,RTVue-XR Avanti)扫描。评估浅表毛细血管丛(SCP)、深部毛细血管丛(DCP)和黄斑无血管区的血管密度(VD)。
COVID-19 PCR检测阳性与眼部检查之间的平均间隔时间为144.6±82.2天。与第2组相比,第1组黄斑和黄斑周围区域SCP和DCP的VD显著降低(p<0.05)。
非重症COVID-19感染可能导致视网膜SCP和DCP的VD降低。