Department of Medicine, Saad Dahlab University, Blida, Algeria.
Department of Zoology, Menofia University, Menofia, Egypt.
Sultan Qaboos Univ Med J. 2023 Nov;23(4):433-439. doi: 10.18295/squmj.5.2023.026. Epub 2023 Nov 30.
This review aimed to compare the potential analgesic effect of forced coughing (FC) with that of local anaesthetics (LA) or placebo during cervical biopsy. A total of 5 electronic databases-Scopus, PubMed, Web of Science, Cochrane Library and Google Scholar-were systematically searched from inception till March 2021. Data were extracted from 6 randomised controlled trials and analysed. During cervical biopsy, the overall effect favoured LA over FC (mean difference [MD] = 1.06, 95% confidence interval [CI]: 0.58 to 1.54; <0.0001). Compared to no pain management, pooled data were comparable between the two groups (MD = -1.2, 95% CI: -3.35 to 0.94; = 0.27). Procedure duration was significantly longer in the LA group than in the FC group (MD = -1.94, 95% CI: -2.47 to -1.41; <0.00001). FC and LA are both useful pain-lowering modalities during cervical biopsy, depending on the setting and their availability.
本综述旨在比较在宫颈活检期间，强制咳嗽（FC）与局部麻醉剂（LA）或安慰剂的潜在镇痛效果。系统地检索了 5 个电子数据库 - Scopus、PubMed、Web of Science、Cochrane Library 和 Google Scholar，从建库开始到 2021 年 3 月进行检索。从 6 项随机对照试验中提取数据并进行分析。在宫颈活检期间，总体效果表明 LA 优于 FC（均数差 [MD] = 1.06，95%置信区间 [CI]：0.58 至 1.54；<0.0001）。与无疼痛管理相比，两组之间的数据具有可比性（MD = -1.2，95%CI：-3.35 至 0.94；= 0.27）。LA 组的手术持续时间明显长于 FC 组（MD = -1.94，95%CI：-2.47 至 -1.41；<0.00001）。FC 和 LA 都是宫颈活检期间降低疼痛的有效方法，具体取决于具体情况及其可用性。
