FiND Programme, Bethlem Royal Hospital, South London and Maudsley NHS Foundation Trust, London, UK.
Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, 16 De Crespigny Park, London, SE5 8AB, UK.
J Neurol. 2024 Apr;271(4):1873-1884. doi: 10.1007/s00415-023-12111-4. Epub 2023 Dec 13.
We report routinely collected outcome data from an 8-week outpatient rehabilitative therapy program. The aims of the intervention were to (1) reduce symptom severity and (2) improve functional mobility in adults with functional neurological disorder (FND).
The program delivered individual physiotherapy, cognitive behavioral therapy (CBT) and self-management sessions, group physiotherapy, and psychoeducation. Outcome measures included the Beck Anxiety Inventory (BAI), Beck Depression Inventory (BDI-II), Work and Social Adjustment Scale (WSAS), 10-Meter Walk Test (10MWT), Timed Up and Go (TUG), and Berg Balance Scale (BBS). Data were analyzed retrospectively in accordance with routine service evaluation. Wilcoxon signed-rank tests assessed changes in outcomes between weeks 1 and 8 for all patients completing treatment (n = 45). For patients who attended the 3-month follow-up (n = 31), Friedman's ANOVA assessed overall change in outcomes over time. Post hoc Wilcoxon signed-rank tests compared pairs of time-points (Weeks 1, 8, and 3-month follow-up).
Analyses of patients completing the program revealed significant improvements in scores between week 1 and week 8. Excluding the BBS, there were statistically significant improvements in all outcomes between weeks 1 and 8 and between weeks 1 and 3-month follow-up.
This outpatient therapy program provided effective treatment for FND. Patients reported reduced anxiety, depression, and functional impairment, as well as improved performance on most physiotherapy measures.
我们报告了一项 8 周门诊康复治疗计划中常规收集的结果数据。该干预的目的是：(1) 减轻症状严重程度，(2) 提高功能性神经障碍（FND）成人的功能移动能力。
该计划提供了个体物理治疗、认知行为疗法（CBT）和自我管理课程、小组物理治疗和心理教育。结果测量包括贝克焦虑量表（BAI）、贝克抑郁量表第二版（BDI-II）、工作和社会适应量表（WSAS）、10 米步行测试（10MWT）、计时起立行走测试（TUG）和伯格平衡量表（BBS）。数据根据常规服务评估进行回顾性分析。对于所有完成治疗的患者（n=45），Wilcoxon 符号秩检验评估了第 1 周到第 8 周的结果变化。对于参加 3 个月随访的患者（n=31），Friedman 的 ANOVA 评估了结果随时间的总体变化。事后 Wilcoxon 符号秩检验比较了两两时间点（第 1、8 和 3 个月随访）。
对完成该计划的患者进行分析发现，第 1 周到第 8 周的评分有显著改善。除 BBS 外，第 1 周到第 8 周和第 1 周到 3 个月随访之间所有结果均有统计学显著改善。
该门诊治疗计划为 FND 提供了有效的治疗。患者报告焦虑、抑郁和功能障碍减轻，以及大多数物理治疗测量的表现改善。
